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Rabbit Anti-COPS4 Antibody (CSB-PA880098ESR2HU)
Supplier: CUSABIO BIOTECH CO.
SGN4 Antibody,Signalosome subunit 4 Antibody,JAB1-containing signalosome subunit 4 Antibody,COPS4 Antibody,CSN4 AntibodyMore alternative names for the antibody
CH4 antibody|COP9 (constitutive photomorphogenic) homolog subunit 4 antibody|COP9 complex homolog subunit 4 antibody|COP9 complex S4 antibody|COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) antibody|COP9 constitutive photomorphogenic homolog subunit 4 antibody|COP9 signalosome complex subunit 4 antibody|COP9 signalosome subunit 4 antibody|COPS4 antibody|CSN complex subunit 4 antibody|CSN4 antibody|CSN4 SCHPO antibody|CSN4_HUMAN antibody|DCH4 antibody|JAB1 containing signalosome subunit 4 antibody|JAB1-containing signalosome subunit 4 antibody|MGC94896 antibody|SGN4 antibody|Signalosome subunit 4 antibody
Anti-COPS4 antibody (ab154223)
Anti-COPS4 antibody (ab154223)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human COP9 signalosome complex subunit 4 protein (1-310AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:422594( Chicken), Entrez Gene:540223( Cow), Entrez Gene:51138( Human), Entrez Gene:26891( Mouse), Entrez Gene:100125960( Pig), Entrez Gene:360915( Rat), Entrez Gene:100037119( Xenopus laevis), Entrez Gene:549469( Xenopus tropicalis ), Entrez Gene:325592( Zebrafish), SwissProt:Q3SZA0( Cow), SwissProt:Q9BT78( Human), SwissProt:O88544( Mouse), SwissProt:A7Y521( Pig), SwissProt:Q68FS2( Rat), SwissProt:Q6P0H6( Zebrafish), Unigene:190384( Human), Unigene:957( Mouse), Unigene:7506( Rat), Unigene:77245( Zebrafish)
|Protein function|| |
Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. .
|Protein sequence and domain|| |
Belongs to the CSN4 family.
|Protein cellular localization|| |
Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.
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|Product type|| |
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