Anti-COPS4 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-COPS4 Antibody (CSB-PA880098ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

SGN4 Antibody,Signalosome subunit 4 Antibody,JAB1-containing signalosome subunit 4 Antibody,COPS4 Antibody,CSN4 Antibody

More alternative names for the antibody
CH4 antibody|COP9 (constitutive photomorphogenic) homolog subunit 4 antibody|COP9 complex homolog subunit 4 antibody|COP9 complex S4 antibody|COP9 constitutive photomorphogenic homolog subunit 4 (Arabidopsis) antibody|COP9 constitutive photomorphogenic homolog subunit 4 antibody|COP9 signalosome complex subunit 4 antibody|COP9 signalosome subunit 4 antibody|COPS4 antibody|CSN complex subunit 4 antibody|CSN4 antibody|CSN4 SCHPO antibody|CSN4_HUMAN antibody|DCH4 antibody|JAB1 containing signalosome subunit 4 antibody|JAB1-containing signalosome subunit 4 antibody|MGC94896 antibody|SGN4 antibody|Signalosome subunit 4 antibody
Anti-COPS4 antibody (ab154223)
Close sc-47644|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-COPS4 Antibody

Catalogue No.

CSB-PA880098ESR2HU

Reactivity

Human

Immunogen

Recombinant human COP9 signalosome complex subunit 4 protein (1-310AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

46 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:422594( Chicken), Entrez Gene:540223( Cow), Entrez Gene:51138( Human), Entrez Gene:26891( Mouse), Entrez Gene:100125960( Pig), Entrez Gene:360915( Rat), Entrez Gene:100037119( Xenopus laevis), Entrez Gene:549469( Xenopus tropicalis ), Entrez Gene:325592( Zebrafish), SwissProt:Q3SZA0( Cow), SwissProt:Q9BT78( Human), SwissProt:O88544( Mouse), SwissProt:A7Y521( Pig), SwissProt:Q68FS2( Rat), SwissProt:Q6P0H6( Zebrafish), Unigene:190384( Human), Unigene:957( Mouse), Unigene:7506( Rat), Unigene:77245( Zebrafish)

Protein function

Component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of the cullin subunits of SCF-type E3 ligase complexes, leading to decrease the Ubl ligase activity of SCF-type complexes such as SCF, CSA or DDB2. Also involved in the deneddylation of non-cullin subunits such as STON2. The complex is also involved in phosphorylation of p53/TP53, c-jun/JUN, IkappaBalpha/NFKBIA, ITPK1, IRF8/ICSBP and SNAPIN, possibly via its association with CK2 and PKD kinases. CSN-dependent phosphorylation of TP53 and JUN promotes and protects degradation by the Ubl system, respectively. .

Protein sequence and domain

Belongs to the CSN4 family.

Protein cellular localization

Cytoplasm. Nucleus. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle.

Research area

All research areas>Signaling Intermediates>CSN
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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