Anti-CRADD Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-CRADD Antibody (CSB-PA005938ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Caspase and RIP adapter with death domain Antibody,RIP-associated protein with a death domain Antibody,CRADD Antibody,RAIDD Antibody

More alternative names for the antibody
CASP2 and RIPK1 domain containing adaptor with death domain antibody|Caspase and RIP adapter with death domain antibody|Caspase and RIP adaptor with death domain antibody|Cradd antibody|CRADD_HUMAN antibody|Death adaptor molecule RAIDD antibody|Death domain containing protein CRADD antibody|Death domain-containing protein CRADD antibody|MGC9163 antibody|RIP associated ICH1/CED3 homologous protein with death domain antibody|RIP associated protein with a death domain antibody|RIP-associated protein with a death domain antibody
Anti-RAIDD antibody [EPR1640Y] (ab52621)
Close sc-374447|sc-374448|sc-7880|sc-377080|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CRADD Antibody

Catalogue No.

CSB-PA005938ESR1HU

Reactivity

Human

Immunogen

Recombinant human Death domain-containing protein CRADD protein (1-199AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

22 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8738( Human), Omim:603454( Human), SwissProt:P78560( Human), Unigene:38533( Human), Unigene:591016( Human)

Protein function

Apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. In the presence of RIP and TRADD, CRADD recruits caspase-2 to the TNFR-1 signalling complex.

Protein tissue specificity

Constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney.

Involvement in disease

Mental retardation, autosomal recessive 34, with variant lissencephaly (MRT34) [MIM:614499]: A disorder characterized by significantly below average general intellectual functioning associated with impairments in adaptive behavior and manifested during the developmental period. MRT34 is a non-syndromic form. Affected individuals have mildly delayed development and significantly impaired cognitive function, precluding independent living and self-care. Speech is rudimentary, but articulate; autism is not present. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Contains a death domain involved in the binding of RIP protein.; The CARD domain mediates the interaction with caspase-2.

Protein cellular localization

Cytoplasm . Nucleus .

Research area

All research areas>Tumor Suppressor/Apoptosis>RAIDD
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!