Anti-CTCFL Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CTCFL Antibody (CSB-PA818824ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Brother of the regulator of imprinted sites Antibody,CCCTC-binding factor Antibody,CTCF paralog Antibody,CTCF-like protein Antibody,Cancer/testis antigen 27 Antibody,CT27 Antibody,Zinc finger protein CTCF-T Antibody,CTCFL Antibody,BORIS Antibody

More alternative names for the antibody
BORIS like protein antibody|Brother of the regulator of imprinted sites antibody|Cancer/testis antigen 27 antibody|CCCTC binding factor (zinc finger protein) like antibody|CCCTC-binding factor antibody|CT27 antibody|CTCF paralog antibody|CTCF T antibody|CTCF-like protein antibody|Ctcfl antibody|CTCFL_HUMAN antibody|dJ579F20.2 antibody|HMG 1L1 antibody|HMGB1L1 antibody|MGC163358 antibody|MGC169105 antibody|MGC169106 antibody|Putative high mobility group protein 1 like 1 antibody|Putative high mobility group protein B1 like 1 antibody|Transcriptional repressor CTCFL antibody|Zinc finger protein CTCF-T antibody
Anti-BORIS antibody [EP12204] (ab187163)
Close sc-135729|sc-135730|sc-51036|sc-377085|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CTCFL Antibody

Catalogue No.

CSB-PA818824ESR2HU

Reactivity

Human

Immunogen

Recombinant human Transcriptional repressor CTCFL protein (1-270AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

75 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:140690( Human), Entrez Gene:664799( Mouse), Entrez Gene:100360757( Rat), Omim:607022( Human), SwissProt:Q8NI51( Human), SwissProt:A2APF3( Mouse), Unigene:131543( Human), Unigene:389396( Mouse)

Protein function

Testis-specific DNA binding protein responsible for insulator function, nuclear architecture and transcriptional control, which probably acts by recruiting epigenetic chromatin modifiers. Plays a key role in gene imprinting in male germline, by participating in the establishment of differential methylation at the IGF2/H19 imprinted control region (ICR). Directly binds the unmethylated H19 ICR and recruits the PRMT7 methyltransferase, leading to methylate histone H4 ‘Arg-3’ to form H4R3sme2. This probably leads to recruit de novo DNA methyltransferases at these sites (By similarity). Seems to act as tumor suppressor. In association with DNMT1 and DNMT3B, involved in activation of BAG1 gene expression by binding to its promoter. Required for dimethylation of H3 lysine 4 (H3K4me2) of MYC and BRCA1 promoters. .

Protein tissue specificity

Testis specific. Specifically expressed in primary spermatocytes.

Protein sequence and domain

Belongs to the CTCF zinc-finger protein family.

Protein cellular localization

Cytoplasm. Nucleus.

Research area

All research areas>Transcription Regulators>BORIS
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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