Anti-CUL5 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CUL5 Antibody (CSB-PA835890ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

CUL-5 Antibody,Vasopressin-activated calcium-mobilizing receptor 1 Antibody,VACM-1 Antibody,CUL5 Antibody,VACM1 Antibody

More alternative names for the antibody
CUL 5 antibody|CUL-5 antibody|CUL5 antibody|CUL5_HUMAN antibody|Cullin-5 (vasopressin-activated calcium-mobilizing receptor-1) antibody|Cullin-5 antibody|Cullin5 antibody|VACM 1 antibody|VACM-1 antibody|VACM1 antibody|Vasopressin activated calcium mobilizing receptor 1 antibody|Vasopressin activated calcium mobilizing receptor antibody|Vasopressin-activated calcium-mobilizing receptor 1 antibody|Vasopressin-activated calcium-mobilizing receptor-1 antibody
Anti-Cullin 5 antibody [EPR14725] (ab184177)
Close sc-373822|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-CUL5 Antibody

Catalogue No.

CSB-PA835890ESR1HU

Reactivity

Human

Immunogen

Recombinant human Cullin-5 protein (1-300AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

90 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:8065( Human), Entrez Gene:75717( Mouse), Entrez Gene:64624( Rat), Omim:601741( Human), SwissProt:Q93034( Human), SwissProt:Q9D5V5( Mouse), SwissProt:Q9JJ31( Rat), Unigene:440320( Human), Unigene:218910( Mouse), Unigene:491606( Mouse), Unigene:163001( Rat)

Protein function

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes, which mediate the ubiquitination and subsequent proteasomal degradation of target proteins. As a scaffold protein may contribute to catalysis through positioning of the substrate and the ubiquitin-conjugating enzyme. The functional specificity of the E3 ubiquitin-protein ligase complex depends on the variable substrate recognition component. ECS(SOCS1) seems to direct ubiquitination of JAK2. Seems to be involved in proteosomal degradation of p53/TP53 stimulated by adenovirus E1B-55 kDa protein. May form a cell surface vasopressin receptor.

Protein sequence and domain

Belongs to the cullin family.

Protein post-translational modifications

Neddylated; which enhances the ubiquitination activity of SCF and prevents binding of the inhibitor CAND1. Deneddylated via its interaction with the COP9 signalosome (CSN). .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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