Anti-CYTH2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-CYTH2 Antibody (CSB-PA857445ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Cytohesin-2 Antibody,ARF exchange factor Antibody,ARF nucleotide-binding site opener Antibody,Protein ARNO Antibody,PH Antibody,SEC7 and coiled-coil domain-containing protein 2 Antibody,CYTH2 Antibody,ARNO Antibody,PSCD2 Antibody,PSCD2L Antibody

More alternative names for the antibody
ARF exchange factor antibody|ARF nucleotide binding site opener antibody|ARF nucleotide-binding site opener antibody|Arno antibody|ARNO protein antibody|CLM2 antibody|CTS18 antibody|CTS18.1 antibody|CYH2_HUMAN antibody|Cyth2 antibody|Cytohesin 2 antibody|Cytohesin-2 antibody|MGC137537 antibody|MGC80440 antibody|PH antibody|PH, SEC7 and coiled-coil domain-containing protein 2 antibody|Pleckstrin homology Sec7 and coiled coil domains 2 antibody|Pleckstrin homology Sec7 and coiled coil domains protein 2 antibody|Protein ARNO antibody|PSCD2 antibody|PSCD2L antibody|PSCD2L, formerly antibody|SEC7 and coiled-coil domain-containing protein 2 antibody|Sec7 antibody|SEC7 homolog B antibody|Sec7B antibody|SEC7L antibody|Sec7p L antibody|Sec7p-like antibody|Sec7pL antibody
Anti-Cytohesin 2 antibody (ab56510)
Close sc-166542|sc-59451|sc-292564|sc-374640|sc-9727|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-CYTH2 Antibody

Catalogue No.

CSB-PA857445ESR2HU

Reactivity

Human

Immunogen

Recombinant human Cytohesin-2 protein (150-350AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

46 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9266( Human), Entrez Gene:116692( Rat), Omim:602488( Human), SwissProt:Q99418( Human), SwissProt:P63035( Rat), Unigene:144011( Human), Unigene:3732( Rat)

Protein function

Acts as a guanine-nucleotide exchange factor (GEF). Promotes guanine-nucleotide exchange on ARF1, ARF3 and ARF6. Promotes the activation of ARF factors through replacement of GDP with GTP. The cell membrane form, in association with ARL4 proteins, recruits ARF6 to the plasma membrane. Involved in neurite growth (By similarity). .

Protein tissue specificity

Widely expressed. .

Protein sequence and domain

Binds via its PH domain to the inositol head group of phosphatidylinositol 1,4,5-trisphosphate. The PH domain is necessary and sufficient for plasma membrane relocalization.; Autoinhibited by its C-terminal basic region.; The coiled coil domain is involved in interaction with CCDC120.

Protein cellular localization

Cell membrane ; Peripheral membrane protein . Cytoplasm . Cell projection . Cell projection, growth cone . Note=Both isoform 1 and isoform 2 are recruited to the cell membrane through its association with ARL4A, ARL4C and ARL4D. They require also interaction with phosphoinositides for targeting to plasma membrane (PubMed:17398095). In differentiating neuroblastoma cells, colocalizes with CCDC120 in both neurite shaft and growth cone areas. .

Research area

All research areas>Signaling Intermediates>cytohesin
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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