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Rabbit Anti-DAZ2 Antibody (CSB-PA623785ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Deleted in azoospermia protein 2 Antibody,DAZ2 AntibodyMore alternative names for the antibody
DAZ2 antibody|DAZ2_HUMAN antibody|DAZ3 antibody|Deleted in azoospermia 2 antibody|Deleted in azoospermia protein 2 antibody|Deleted in azoospermia protein 3 antibody|MGC126442 antibody|pDP1678 antibody
Anti-DAZ2 antibody (ab97772)
Anti-DAZ2 antibody (ab97772)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Deleted in azoospermia protein 2 protein (1-200AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=57055" target="_blank">Entrez Gene:57055( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/400026" target="_blank">Omim:400026( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q13117" target="_blank">SwissProt:Q13117( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=592257" target="_blank">Unigene:592257( Human)</a>
|Protein function|| |
RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3'-UTR of mRNAs and regulating their translation.
|Protein tissue specificity|| |
Testis specific. .
|Involvement in disease|| |
Spermatogenic failure Y-linked 2 (SPGFY2) [MIM:415000]: A disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. . Note=The disease may be caused by mutations affecting the gene represented in this entry. AZFc deletions in the Yq11.23 region including the DAZ genes are the most common known genetic cause of human male infertility.
|Protein sequence and domain|| |
Belongs to the RRM DAZ family. The DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.
|Protein cellular localization|| |
Cytoplasm . Nucleus . Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.
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CUSABIO BIOTECH CO.
|Product type|| |
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