Anti-DAZ2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-DAZ2 Antibody (CSB-PA623785ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Deleted in azoospermia protein 2 Antibody,DAZ2 Antibody

More alternative names for the antibody
DAZ2 antibody|DAZ2_HUMAN antibody|DAZ3 antibody|Deleted in azoospermia 2 antibody|Deleted in azoospermia protein 2 antibody|Deleted in azoospermia protein 3 antibody|MGC126442 antibody|pDP1678 antibody
Anti-DAZ2 antibody (ab97772)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-DAZ2 Antibody

Catalogue No.

CSB-PA623785ESR1HU

Reactivity

Human

Immunogen

Recombinant human Deleted in azoospermia protein 2 protein (1-200AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

63 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:57055( Human), Omim:400026( Human), SwissProt:Q13117( Human), Unigene:592257( Human)

Protein function

RNA-binding protein that plays an essential role in spermatogenesis. May act by binding to the 3′-UTR of mRNAs and regulating their translation.

Protein tissue specificity

Testis specific. .

Involvement in disease

Spermatogenic failure Y-linked 2 (SPGFY2) [MIM:415000]: A disorder resulting in the absence (azoospermia) or reduction (oligozoospermia) of sperm in the semen, leading to male infertility. . Note=The disease may be caused by mutations affecting the gene represented in this entry. AZFc deletions in the Yq11.23 region including the DAZ genes are the most common known genetic cause of human male infertility.

Protein sequence and domain

Belongs to the RRM DAZ family. The DAZ-like repeats are essential and mediate the interaction with DAZAP1 and DAZAP2.

Protein cellular localization

Cytoplasm . Nucleus . Note=Predominantly cytoplasmic. Nuclear at some stages of spermatozoide development. Localizes both to the nuclei and cytoplasm of spermatozoide differentiation. Nuclear in fetal gonocytes and in spermatogonial nuclei. It then relocates to the cytoplasm during male meiosis.

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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