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Rabbit Anti-DEDD Antibody (CSB-PA006648ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Death effector domain-containing protein Antibody,DEDPro1 Antibody,Death effector domain-containing testicular molecule Antibody,FLDED-1 Antibody,DEDD Antibody,DEDPRO1 Antibody,DEFT Antibody,KE05 AntibodyMore alternative names for the antibody
CASP8IP1 antibody|Death effector domain containing antibody|Death effector domain containing protein antibody|Death effector domain containing testicular molecule antibody|Death effector domain-containing protein antibody|Death effector domain-containing testicular molecule antibody|DEDD 1 antibody|dedD antibody|DEDD_HUMAN antibody|DEDD1 antibody|DEDPro 1 antibody|DEDPro1 antibody|DEFT antibody|FLDED 1 antibody|FLDED-1 antibody|FLDED1 antibody|KE 05 antibody|KE05 antibody|OTTHUMP00000031822 antibody
Anti-DEDD antibody (ab203655)
Anti-DEDD antibody (ab203655)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Death effector domain-containing protein (1-318AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:9191( Human), Entrez Gene:21945( Mouse), Entrez Gene:83631( Rat), Omim:606841( Human), SwissProt:O75618( Human), SwissProt:Q9Z1L3( Mouse), SwissProt:Q9Z2K0( Rat), Unigene:146406( Human), Unigene:270139( Mouse), Unigene:203286( Rat)
|Protein function|| |
A scaffold protein that directs CASP3 to certain substrates and facilitates their ordered degradation during apoptosis. May also play a role in mediating CASP3 cleavage of KRT18. Regulates degradation of intermediate filaments during apoptosis. May play a role in the general transcription machinery in the nucleus and might be an important regulator of the activity of GTF3C3. Inhibits DNA transcription in vitro (By similarity). .
|Protein tissue specificity|| |
Widely expressed with highest levels in testis. .
|Protein post-translational modifications|| |
Exists predominantly in a mono- or diubiquitinated form.
|Protein cellular localization|| |
Cytoplasm. Nucleus, nucleolus . Note=Translocated to the nucleus during CD95-mediated apoptosis where it is localized in the nucleoli (By similarity). Following apoptosis induction, the mono and/or diubiquitination form increases and forms filamentous structures that colocalize with KRT8 and KRT18 intermediate filament network in simple epithelial cells. .
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CUSABIO BIOTECH CO.
|Product type|| |
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