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Rabbit Anti-DHCR24 Antibody (CSB-PA618005ESR2HU)
Supplier: CUSABIO BIOTECH CO.
24-dehydrocholesterol reductase Antibody,3-beta-hydroxysterol delta-24-reductase Antibody,Diminuto/dwarf1 homolog Antibody,Seladin-1 Antibody,DHCR24 AntibodyMore alternative names for the antibody
24 dehydrocholesterol reductase antibody|24-dehydrocholesterol reductase antibody|3 beta hydroxysterol delta 24 reductase antibody|3-beta-hydroxysterol delta-24-reductase antibody|DCE antibody|Delta(24)-sterol reductase antibody|Desmosterol to cholesterol enzyme antibody|DHC24_HUMAN antibody|Dhcr24 antibody|Diminuto dwarf1 homolog antibody|Diminuto/dwarf1 homolog antibody|KIAA0018 antibody|Nbla03646 antibody|Seladin-1 antibody|SELADIN1 antibody|Selective AD indicator 1 antibody|Selective Alzheimer’s Disease Indicator 1 antibody
Anti-Seladin 1 antibody (ab40490)
Anti-Seladin 1 antibody (ab40490)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Delta (24)-sterol reductase protein (227-516AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:1718( Human), Entrez Gene:74754( Mouse), Entrez Gene:298298( Rat), Omim:606418( Human), SwissProt:Q15392( Human), SwissProt:Q8VCH6( Mouse), SwissProt:Q5BQE6( Rat), Unigene:498727( Human), Unigene:133370( Mouse), Unigene:225146( Rat)
|Protein function|| |
Catalyzes the reduction of the delta-24 double bond of sterol intermediates. Protects cells from oxidative stress by reducing caspase 3 activity during apoptosis induced by oxidative stress. Also protects against amyloid-beta peptide-induced apoptosis. .
|Protein tissue specificity|| |
Highly expressed in brain and adrenal gland with moderate expression in liver, lung, spleen, prostate and spinal cord. Low expression in heart, uterus and prostate. Undetectable in blood cells. In the brain, strongly expressed in cortical regions, substantia nigra, caudate nucleus, hippocampus, medulla oblongata and pons. In brains affected by Alzheimer disease, expression in the inferior temporal lobe is substantially lower than in the frontal cortex. .
|Involvement in disease|| |
Desmosterolosis (DESMOS) [MIM:602398]: Rare autosomal recessive disorder characterized by multiple congenital anomalies and elevated levels of the cholesterol precursor desmosterol in plasma, tissue, and cultured cells. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the FAD-binding oxidoreductase/transferase type 4 family.
|Protein cellular localization|| |
Endoplasmic reticulum membrane; Single-pass membrane protein. Golgi apparatus membrane; Single-pass membrane protein.
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CUSABIO BIOTECH CO.
|Product type|| |
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