Anti-DHRS2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-DHRS2 Antibody (CSB-PA615674ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Dicarbonyl reductase HEP27 Antibody,Protein D Antibody,DHRS2 Antibody

More alternative names for the antibody
5430405K24Rik antibody|Dehydrogenase/reductase (SDR family) member 2 antibody|Dehydrogenase/reductase member 2 antibody|Dehydrogenase/reductase SDR family member 2 antibody|Dehydrogenase/reductase SDR family member 2 mitochondria antibody|Dicarbonyl reductase HEP27 antibody|Hep27 antibody|HEP27 protein antibody|MGC143467 antibody|Protein D antibody|SDR family member antibody|SDR25C1 antibody|Short chain alcohol dehydrogenase family member antibody|Short chain dehydrogenase/reductase family 25C member 1 antibody
Anti-DHRS2 antibody (ab83254)
Close sc-517054|sc-104879|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-DHRS2 Antibody

Catalogue No.

CSB-PA615674ESR2HU

Reactivity

Human

Immunogen

Recombinant human Dehydrogenase/reductase SDR family member 2, mitochondrial protein (1-300AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

29 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10202( Human), Entrez Gene:71412( Mouse), Entrez Gene:691464( Rat), Omim:615194( Human), SwissProt:Q13268( Human), Unigene:272499( Human)

Protein function

Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. .

Protein tissue specificity

Widely expressed, with highest levels in liver and kidney, followed by heart, spleen, skeletal muscle and placenta. In hemopoietic cells, expressed in dendritic cells, but not in monocytes, macrophages, granulocytes, nor in B and T lymphocytes. .

Protein sequence and domain

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein cellular localization

Mitochondrion matrix. Nucleus. Note=A minor fraction of the protein is translocated from the mitochondria to the nucleus, after cleavage of the targeting signal.

Research area

All research areas>Synthesis and Degradation>DHRS
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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