No products in the cart.
Rabbit Anti-DHRS2 Antibody (CSB-PA615674ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Dicarbonyl reductase HEP27 Antibody,Protein D Antibody,DHRS2 AntibodyMore alternative names for the antibody
5430405K24Rik antibody|Dehydrogenase/reductase (SDR family) member 2 antibody|Dehydrogenase/reductase member 2 antibody|Dehydrogenase/reductase SDR family member 2 antibody|Dehydrogenase/reductase SDR family member 2 mitochondria antibody|Dicarbonyl reductase HEP27 antibody|Hep27 antibody|HEP27 protein antibody|MGC143467 antibody|Protein D antibody|SDR family member antibody|SDR25C1 antibody|Short chain alcohol dehydrogenase family member antibody|Short chain dehydrogenase/reductase family 25C member 1 antibody
Anti-DHRS2 antibody (ab83254)
Anti-DHRS2 antibody (ab83254)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Dehydrogenase/reductase SDR family member 2, mitochondrial protein (1-300AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=10202" target="_blank">Entrez Gene:10202( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=71412" target="_blank">Entrez Gene:71412( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=691464" target="_blank">Entrez Gene:691464( Rat)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/615194" target="_blank">Omim:615194( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q13268" target="_blank">SwissProt:Q13268( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=272499" target="_blank">Unigene:272499( Human)</a>
|Protein function|| |
Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sugars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resulting in the accumulation of MDM2 and CDKN1A/p21. .
|Protein tissue specificity|| |
Widely expressed, with highest levels in liver and kidney, followed by heart, spleen, skeletal muscle and placenta. In hemopoietic cells, expressed in dendritic cells, but not in monocytes, macrophages, granulocytes, nor in B and T lymphocytes. .
|Protein sequence and domain|| |
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
|Protein cellular localization|| |
Mitochondrion matrix. Nucleus. Note=A minor fraction of the protein is translocated from the mitochondria to the nucleus, after cleavage of the targeting signal.
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Synthesis-and-Degradation/">Synthesis and Degradation</a>><a href="https://antibodyplus.com/product-tag/DHRS/">DHRS</a><br><a href="https://antibodyplus.com/product-tag/Synthesis-and-Degradation/"> (View all antibody categories related to Synthesis and Degradation)</a>
AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.
CUSABIO BIOTECH CO.
|Product type|| |
There are no reviews for this product yet.
By submitting a review, get following benefits:
1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!
There is no extra validation for this product yet.
Check other extra validated antibodies below: