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Rabbit Anti-DHTKD1 Antibody (CSB-PA842685ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1 Antibody,mitochondrial Antibody,Dehydrogenase E1 and transketolase domain-containing protein 1 Antibody,DHTKD1 Antibody,KIAA1630 AntibodyMore alternative names for the antibody
Dehydrogenase E1 and transketolase domain containing 1 antibody|Dehydrogenase E1 and transketolase domain containing protein 1 antibody|Dehydrogenase E1 and transketolase domain-containing protein 1 antibody|DHTK1_HUMAN antibody|dhtkd1 antibody|DKFZp762M115 antibody|KIAA1630 antibody|MGC3090 antibody|Probable 2 oxoglutarate dehydrogenase E1 component DHKTD1 mitochondrial antibody|Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial antibody
Anti-DHTKD1 antibody (ab107056)
Anti-DHTKD1 antibody (ab107056)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Probable 2-oxoglutarate dehydrogenase E1 component DHKTD1, mitochondrial protein (1-280AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=55526" target="_blank">Entrez Gene:55526( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=209692" target="_blank">Entrez Gene:209692( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov:80/entrez/query.fcgi?SUBMIT=y&db=nucleotide&term=BC007955" target="_blank">GenBank:BC007955( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q96HY7" target="_blank">SwissProt:Q96HY7( Human)</a>, <a href="http://www.uniprot.org/uniprot/A2ATU0" target="_blank">SwissProt:A2ATU0( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=104980" target="_blank">Unigene:104980( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=711138" target="_blank">Unigene:711138( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=222517" target="_blank">Unigene:222517( Mouse)</a>
|Protein function|| |
The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2). It contains multiple copies of three enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3) (By similarity). .
|Involvement in disease|| |
Charcot-Marie-Tooth disease 2Q (CMT2Q) [MIM:615025]: An axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. Nerve conduction velocities are normal or slightly reduced. . Note=The disease is caused by mutations affecting the gene represented in this entry.; 2-aminoadipic 2-oxoadipic aciduria (AMOXAD) [MIM:204750]: A metabolic disorder characterized by increased levels of 2-oxoadipate and 2-hydroxyadipate in the urine, and elevated 2-aminoadipate in the plasma. Patients can have mild to severe intellectual disability, muscular hypotonia, developmental delay, ataxia, and epilepsy. Most cases are asymptomatic. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the alpha-ketoglutarate dehydrogenase family.
|Protein cellular localization|| |
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Synthesis-and-Degradation/">Synthesis and Degradation</a>><a href="https://antibodyplus.com/product-tag/DHTKD1/">DHTKD1</a><br><a href="https://antibodyplus.com/product-tag/Synthesis-and-Degradation/"> (View all antibody categories related to Synthesis and Degradation)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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