Anti-DPYS Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-DPYS Antibody (CSB-PA007169ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Dihydropyrimidinase Antibody,Dihydropyrimidine amidohydrolase Antibody,Hydantoinase Antibody,DPYS Antibody

More alternative names for the antibody
DHP antibody|DHPase antibody|Dihydropyrimidinase antibody|Dihydropyrimidine amidohydrolase antibody|Dpys antibody|DPYS_HUMAN antibody|Hydantoinase antibody
Anti-DPYD antibody (ab54797)
Close sc-376712|sc-34065|sc-271308|sc-376681|sc-50521|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-DPYS Antibody

Catalogue No.

CSB-PA007169ESR2HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Dihydropyrimidinase protein (250-519AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

56 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1806( Human), GenBank:AAH08379( Human), Omim:274270( Human), Omim:612779( Human), SwissProt:Q12882( Human), Unigene:335034( Human)

Protein function

Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6-dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate.

Protein tissue specificity

Liver and kidney.

Involvement in disease

Dihydropyrimidinase deficiency (DPYSD) [MIM:222748]: An autosomal recessive disorder of pyrimidine metabolism characterized by dihydropyrimidinuria. It is associated with a variable clinical phenotype characterized by epileptic or convulsive attacks, dysmorphic features and severe developmental delay, and congenital microvillous atrophy. Most patients are, however, asymptomatic. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the DHOase family. Hydantoinase/dihydropyrimidinase subfamily.

Protein post-translational modifications

Carbamylation allows a single lysine to coordinate two zinc ions. .

Research area

All research areas>Synthesis and Degradation>DPYD
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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