Anti-DSC2 Antibody

$99.00$319.00

Reactivity: Human,Rat
Applications: ELISA,WB
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-DSC2 Antibody (CSB-PA007190ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Desmocollin-2 Antibody,Cadherin family member 2 Antibody,Desmocollin-3 Antibody,Desmosomal glycoprotein II Antibody,Desmosomal glycoprotein III Antibody,DSC2 Antibody,CDHF2 Antibody,DSC3 Antibody

More alternative names for the antibody
ARVD11 antibody|CDHF2 antibody|CDHF3 antibody|Desmocollin 2 antibody|Desmocollin 3 antibody|Desmosomal glycoprotein II and III antibody|DG2 antibody|DGII/III antibody|DSC antibody|DSC1 antibody|DSC2 antibody|DSC3 antibody|DSC4 antibody
Anti-Desmocollin 2 antibody (ab95967)
Close sc-34311|sc-34307|

Recommended applications: ELISA, WB

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-DSC2 Antibody

Catalogue No.

CSB-PA007190ESR1HU

Reactivity

Human, Rat

Immunogen

Recombinant human Desmocollin-2 protein (520-690AA)

Host

Rabbit

Applications

ELISA, WB

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

99 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1824( Human), Omim:125645( Human), SwissProt:Q02487( Human), Unigene:95612( Human)

Protein function

Component of intercellular desmosome junctions. Involved in the interaction of plaque proteins and intermediate filaments mediating cell-cell adhesion. May contribute to epidermal cell positioning (stratification) by mediating differential adhesiveness between cells that express different isoforms.

Protein tissue specificity

Expressed in epithelia, myocardium and lymph nodes.

Involvement in disease

Arrhythmogenic right ventricular dysplasia, familial, 11 (ARVD11) [MIM:610476]: A congenital heart disease characterized by infiltration of adipose and fibrous tissue into the right ventricle and loss of myocardial cells, resulting in ventricular and supraventricular arrhythmias. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Calcium may be bound by the cadherin-like repeats.; Three calcium ions are usually bound at the interface of each cadherin domain and rigidify the connections, imparting a strong curvature to the full-length ectodomain.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein . Cell junction, desmosome .

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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