Anti-DSTYK Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-DSTYK Antibody (CSB-PA007213ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Dual serine/threonine and tyrosine protein kinase Antibody,Dusty protein kinase Antibody,Dusty PK Antibody,RIP-homologous kinase Antibody,Receptor-interacting serine/threonine-protein kinase 5 Antibody,Sugen kinase 496 Antibody,SgK496 Antibody,DSTYK Antibody,KIAA0472 Antibody,RIP5 Antibody,RIPK5 Antibody,SGK496 Antibody,HDCMD38P Antibody

More alternative names for the antibody
DSTYK antibody|Dual serine/threonine and tyrosine protein kinase antibody|Dusty PK antibody|Dusty protein kinase antibody|DUSTY_HUMAN antibody|HDCMD38P antibody|KIAA0472 antibody|Receptor interacting protein 5 antibody|Receptor interacting protein kinase 5 antibody|Receptor interacting serine/threonine protein kinase 5 antibody|Receptor-interacting serine/threonine-protein kinase 5 antibody|RIP homologous kinase antibody|RIP-homologous kinase antibody|RIP5 antibody|RIPK5 antibody|SgK496 antibody|Sugen kinase 496 antibody
Anti-RIPK5 antibody (ab153997)
Close sc-374487|sc-162109|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-DSTYK Antibody

Catalogue No.

CSB-PA007213ESR2HU

Reactivity

Human

Immunogen

Recombinant human Dual serine/threonine and tyrosine protein kinase protein (680-929AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

105 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:25778( Human), Omim:612666( Human), SwissProt:Q6XUX3( Human), Unigene:6874( Human)

Protein function

Acts as a positive regulator of ERK phosphorylation downstream of fibroblast growth factor-receptor activation. May induce both caspase-dependent apoptosis and caspase-independent cell death. .

Protein tissue specificity

Predominantly expressed in skeletal muscle and testis. Expressed in basolateral and apical membranes of all tubular epithelia. Expressed in thin ascending limb of the loop of Henle and the distal convoluted tubule. Expressed in all layers of transitional ureteric epithelium and in the ureteric smooth-muscle cells. Weakly expressed in heart, brain, placenta, kidney, pancreas, spleen, thymus, prostate, uterus, small intestine, white blood cells, stomach, spinal cord and adrenal gland. Is widely distributed in the CNS. Also detected in several tumor cell lines. .

Involvement in disease

Congenital anomalies of the kidney and urinary tract 1 (CAKUT1) [MIM:610805]: A disorder encompassing a broad spectrum of renal and urinary tract malformations that include renal agenesis, kidney hypodysplasia, multicystic kidney dysplasia, duplex collecting system, posterior urethral valves and ureter abnormalities. Congenital anomalies of kidney and urinary tract are the commonest cause of chronic kidney disease in children. . Note=Disease susceptibility is associated with variations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Protein cellular localization

Cytoplasm . Cell membrane . Apical cell membrane . Basolateral cell membrane . Cell junction . Note=Detected at apical cell-cell junctions. Colocalized with FGF receptors to the cell membrane (By similarity). Detected in basolateral and apical membranes of all tubular epithelia. .

Research area

All research areas>Kinases and Phosphatases>RIP
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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