Anti-DVL2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-DVL2 Antibody (CSB-PA007286ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Dishevelled-2 Antibody,DSH homolog 2 Antibody,DVL2 Antibody

More alternative names for the antibody
Dishevelled 2 (homologous to Drosophila dsh) antibody|Dishevelled dsh homolog 2 antibody|dishevelled segment polarity protein 2 antibody|Dishevelled-2 antibody|Dishevelled2 antibody|DSH homolog 2 antibody|DVL 2 antibody|Dvl2 antibody|DVL2_HUMAN antibody|Segment polarity protein dishevelled homolog DVL 2 antibody|Segment polarity protein dishevelled homolog DVL-2 antibody|Segment polarity protein dishevelled homolog DVL2 antibody
Anti-Dishevelled 2 antibody (ab137528)
Close sc-166303|sc-7397|sc-7400|sc-25534|sc-8025|sc-133525|sc-8026|sc-271319|sc-393374|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-DVL2 Antibody

Catalogue No.

CSB-PA007286ESR2HU

Reactivity

Human

Immunogen

Recombinant human Segment polarity protein dishevelled homolog DVL-2 protein (1-240AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

78 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1856( Human), Entrez Gene:13543( Mouse), Entrez Gene:303251( Rat), Omim:602151( Human), SwissProt:O14641( Human), SwissProt:Q60838( Mouse), Unigene:118640( Human), Unigene:5114( Mouse), Unigene:153569( Rat)

Protein function

Plays a role in the signal transduction pathways mediated by multiple Wnt genes. Participates both in canonical and non-canonical Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. .

Protein sequence and domain

Belongs to the DSH family. The DIX domain mediates homooligomerization.

Protein post-translational modifications

Phosphorylated by CSNK1D (PubMed:21422228, PubMed:9192851). WNT3A induces DVL2 phosphorylation by CSNK1E and MARK kinases (PubMed:25805136). .

Protein cellular localization

Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Cytoplasm, cytosol . Cytoplasmic vesicle . Nucleus . Note=Localizes at the cell membrane upon interaction with frizzled family members and promotes their internalization. Localizes to cytoplasmic puncta (By similarity). Interaction with FOXK1 and FOXK2 induces nuclear translocation (PubMed:25805136). .

Research area

All research areas>Signaling Intermediates>Dishevelled
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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