Anti-DYNC2LI1 Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-DYNC2LI1 Antibody (CSB-PA844722ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Cytoplasmic dynein 2 light intermediate chain 1 Antibody,Dynein 2 light intermediate chain Antibody,DYNC2LI1 Antibody,D2LIC Antibody,LIC3 Antibody,CGI-60 Antibody

More alternative names for the antibody
CGI-60 antibody|Cytoplasmic dynein 2 light intermediate chain 1 antibody|D2LIC antibody|DC2L1_HUMAN antibody|DYNC2LI1 antibody|Dynein 2 light intermediate chain antibody|Dynein, cytoplasmic 2, light intermediate chain 1 antibody|LIC3 antibody
Anti-DC2L1 antibody – C-terminal (ab177974)
Close sc-376645|sc-376644|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-DYNC2LI1 Antibody

Catalogue No.

CSB-PA844722ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Cytoplasmic dynein 2 light intermediate chain 1 protein (1-352AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

39 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:507311( Cow), Entrez Gene:51626( Human), Entrez Gene:213575( Mouse), Entrez Gene:298767( Rat), SwissProt:Q32KV4( Cow), SwissProt:Q8TCX1( Human), SwissProt:Q8K0T2( Mouse), SwissProt:Q6AY43( Rat), Unigene:371597( Human), Unigene:246119( Mouse), Unigene:12074( Rat)

Protein function

Required for correct intraflagellar transport (IFT), the bi-directional movement of particles required for the assembly, maintenance and functioning of primary cilia. Involved in the regulation of ciliary length. .

Protein tissue specificity

Expressed in bone, brain, kidney, and cartilage (PubMed:26077881, PubMed:26130459). Lower expression in heart, liver, lung, placenta and thymus (PubMed:26077881). .

Involvement in disease

Short-rib thoracic dysplasia 15 with polydactyly (SRTD15) [MIM:617088]: A form of short-rib thoracic dysplasia, a group of autosomal recessive ciliopathies that are characterized by a constricted thoracic cage, short ribs, shortened tubular bones, and a ‘trident’ appearance of the acetabular roof. Polydactyly is variably present. Non-skeletal involvement can include cleft lip/palate as well as anomalies of major organs such as the brain, eye, heart, kidneys, liver, pancreas, intestines, and genitalia. Some forms of the disease are lethal in the neonatal period due to respiratory insufficiency secondary to a severely restricted thoracic cage, whereas others are compatible with life. Disease spectrum encompasses Ellis-van Creveld syndrome, asphyxiating thoracic dystrophy (Jeune syndrome), Mainzer-Saldino syndrome, and short rib-polydactyly syndrome. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the dynein light intermediate chain family.

Protein cellular localization

Cytoplasm . Cell projection, cilium . Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, cilium axoneme . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Note=Localizes to the apical cytoplasm. .

Research area

All research areas>Structural Proteins>DYNC2
(View all antibody categories related to Structural Proteins)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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