Anti-E2F6 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-E2F6 Antibody (CSB-PA007347ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

E2F-6 Antibody,E2F6 Antibody

More alternative names for the antibody
E2F 6 antibody|E2F binding site modulating activity protein antibody|E2F transcription factor 6 antibody|E2F transcription factor 6 isoform 1 antibody|E2F-6 antibody|E2F6 antibody|E2F6_HUMAN antibody|EMA antibody|MGC111545 antibody|Transcription factor E2F6 antibody
Anti-E2F6 antibody – ChIP Grade (ab53061)
Close sc-390022|sc-22823|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-E2F6 Antibody

Catalogue No.

CSB-PA007347ESR2HU

Reactivity

Human

Immunogen

Recombinant human Transcription factor E2F6 protein (1-281AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

31 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1876( Human), Entrez Gene:50496( Mouse), Omim:602944( Human), SwissProt:O75461( Human), SwissProt:O54917( Mouse), Unigene:603093( Human), Unigene:23296( Mouse)

Protein function

Inhibitor of E2F-dependent transcription. Binds DNA cooperatively with DP proteins through the E2 recognition site, 5′-TTTC[CG]CGC-3′. Has a preference for the 5′-TTTCCCGC-3′ E2F recognition site. E2F6 lacks the transcriptional activation and pocket protein binding domains. Appears to regulate a subset of E2F-dependent genes whose products are required for entry into the cell cycle but not for normal cell cycle progression. May silence expression via the recruitment of a chromatin remodeling complex containing histone H3-K9 methyltransferase activity. Overexpression delays the exit of cells from the S-phase.

Protein tissue specificity

Expressed in all tissues examined. Highest levels in placenta, skeletal muscle, heart, ovary, kidney, small intestine and spleen.

Protein sequence and domain

Belongs to the E2F/DP family.

Protein cellular localization

Nucleus.

Research area

All research areas>Transcription Regulators>E2F
(View all antibody categories related to Transcription Regulators)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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