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Rabbit Anti-ECE1 Antibody (CSB-PA007371ESR2HU)
Supplier: CUSABIO BIOTECH CO.
ECE-1 Antibody,ECE1 AntibodyMore alternative names for the antibody
ECE 1 antibody|ECE antibody|ECE-1 antibody|ECE1 antibody|ECE1_HUMAN antibody|Endothelin converting enzyme 1 antibody|Endothelin-converting enzyme 1 antibody
Anti-ECE1 antibody (ab71829)
Anti-ECE1 antibody (ab71829)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Endothelin-converting enzyme 1 protein (471-770AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:281133( Cow), Entrez Gene:100719142( Guinea pig), Entrez Gene:1889( Human), Entrez Gene:230857( Mouse), Entrez Gene:94204( Rat), Omim:600423( Human), SwissProt:P42891( Cow), SwissProt:P97739( Guinea pig), SwissProt:P42892( Human), SwissProt:Q4PZA2( Mouse), SwissProt:P42893( Rat), Unigene:195080( Human), Unigene:401062( Mouse), Unigene:483336( Mouse), Unigene:7000( Rat)
|Protein function|| |
Converts big endothelin-1 to endothelin-1. .
|Protein tissue specificity|| |
All isoforms are expressed in umbilical vein endothelial cells, polynuclear neutrophils, fibroblasts, atrium cardiomyocytes and ventricles. Isoforms A, B and C are also expressed in placenta, lung, heart, adrenal gland and phaeochromocytoma; isoforms A and C in liver, testis and small intestine; isoform B, C and D in endothelial cells and umbilical vein smooth muscle cells; isoforms C and D in saphenous vein cells, and isoform C in kidney. .
|Involvement in disease|| |
Hirschsprung disease, cardiac defects, and autonomic dysfunction (HCAD) [MIM:613870]: A disorder characterized by skip-lesions Hirschsprung disease, craniofacial abnormalities and other dysmorphic features, cardiac defects including ductus arteriosus, small subaortic ventricular septal defect, small atrial septal defect, and autonomic dysfunction. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the peptidase M13 family.
|Protein cellular localization|| |
Cell membrane; Single-pass type II membrane protein.
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CUSABIO BIOTECH CO.
|Product type|| |
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