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Rabbit Anti-EFNB1 Antibody (CSB-PA007465ESR1HU)
Supplier: CUSABIO BIOTECH CO.
EFL-3 Antibody,ELK ligand Antibody,ELK-L Antibody,EPH-related receptor tyrosine kinase ligand 2 Antibody,LERK-2 Antibody,EFNB1 Antibody,EFL3 Antibody, EPLG2 Antibody,LERK2 AntibodyMore alternative names for the antibody
CEK5 ligand antibody|Ephrin B1 antibody|Ephrin B2 antibody|LERK2 antibody
Anti-Ephrin B antibody (ab55352)
Anti-Ephrin B antibody (ab55352)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Ephrin-B1 protein (28-237AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:1947( Human), Entrez Gene:1948( Human), Entrez Gene:13641( Mouse), Entrez Gene:13642( Mouse), Entrez Gene:25186( Rat), Omim:300035( Human), Omim:600527( Human), SwissProt:P52799( Human), SwissProt:P98172( Human), SwissProt:P52795( Mouse), SwissProt:P52800( Mouse), SwissProt:P52796( Rat), SwissProt:Q6P7B6( Rat), Unigene:144700( Human), Unigene:149239( Human), Unigene:44398( Rat)
|Protein function|| |
Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). .; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). .
|Protein tissue specificity|| |
Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas.
|Involvement in disease|| |
Craniofrontonasal syndrome (CFNS) [MIM:304110]: X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the ephrin family.
|Protein post-translational modifications|| |
Inducible phosphorylation of tyrosine residues in the cytoplasmic domain. .
|Protein cellular localization|| |
Membrane; Single-pass type I membrane protein.
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CUSABIO BIOTECH CO.
|Product type|| |
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