Anti-EFNB1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-EFNB1 Antibody (CSB-PA007465ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

EFL-3 Antibody,ELK ligand Antibody,ELK-L Antibody,EPH-related receptor tyrosine kinase ligand 2 Antibody,LERK-2 Antibody,EFNB1 Antibody,EFL3 Antibody, EPLG2 Antibody,LERK2 Antibody

More alternative names for the antibody
CEK5 ligand antibody|Ephrin B1 antibody|Ephrin B2 antibody|LERK2 antibody
Anti-Ephrin B antibody (ab55352)
Close sc-19227|sc-398735|sc-15397|sc-1010|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-EFNB1 Antibody

Catalogue No.

CSB-PA007465ESR1HU

Reactivity

Human

Immunogen

Recombinant human Ephrin-B1 protein (28-237AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

38 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:1947( Human), Entrez Gene:1948( Human), Entrez Gene:13641( Mouse), Entrez Gene:13642( Mouse), Entrez Gene:25186( Rat), Omim:300035( Human), Omim:600527( Human), SwissProt:P52799( Human), SwissProt:P98172( Human), SwissProt:P52795( Mouse), SwissProt:P52800( Mouse), SwissProt:P52796( Rat), SwissProt:Q6P7B6( Rat), Unigene:144700( Human), Unigene:149239( Human), Unigene:44398( Rat)

Protein function

Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). .; Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds to the receptor tyrosine kinases EPHB3 (preferred), EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity). .

Protein tissue specificity

Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas.

Involvement in disease

Craniofrontonasal syndrome (CFNS) [MIM:304110]: X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the ephrin family.

Protein post-translational modifications

Inducible phosphorylation of tyrosine residues in the cytoplasmic domain. .

Protein cellular localization

Membrane; Single-pass type I membrane protein.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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