Anti-EIF3F Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

Clear
-$50 as credit for submitting review for primary antibody
Shipping notice:
Product will be delivered in 6 to 8 Business Days

Rabbit Anti-EIF3F Antibody (CSB-PA007535ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Eukaryotic translation initiation factor 3 subunit F Antibody,Deubiquitinating enzyme eIF3f Antibody,Eukaryotic translation initiation factor 3 subunit 5 Antibody,EIF3F Antibody

More alternative names for the antibody
Deubiquitinating enzyme eIF3f antibody|eIF 3 epsilon antibody|eIF-3-epsilon antibody|eIF3 p47 antibody|eIF3 p47 subunit antibody|eIF3-epsilon antibody|eIF3-p47 antibody|eIF3f antibody|EIF3F_HUMAN antibody|EIF3S5 antibody|EIF3S5, formerly antibody|Eukaryotic translation initiation factor 3 subunit 5 antibody|Eukaryotic translation initiation factor 3 subunit 5, formerly antibody|Eukaryotic translation initiation factor 3 subunit F antibody|eukaryotic translation initiation factor 3, subunit 5 (epsilon, 47kD) antibody|eukaryotic translation initiation factor 3, subunit 5 epsilon, 47kDa antibody|eukaryotic translation initiation factor 3, subunit F antibody|translation initiation factor 3 47 kda subunit antibody
Anti-EIF3F antibody (ab64177)
Close sc-390831|sc-390413|sc-368393|sc-30247|sc-514292|sc-30248|sc-16378|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-EIF3F Antibody

Catalogue No.

CSB-PA007535ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Eukaryotic translation initiation factor 3 subunit F protein (88-357AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

37 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:451007( Chimpanzee), Entrez Gene:8665( Human), Entrez Gene:66085( Mouse), Entrez Gene:293427( Rat), Omim:603914( Human), SwissProt:A5A6I3( Chimpanzee), SwissProt:Q4R5B8( Cynomolgus Monkey), SwissProt:O00303( Human), SwissProt:Q9DCH4( Mouse), Unigene:516023( Human), Unigene:182962( Mouse), Unigene:41724( Rat)

Protein function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). .; Deubiquitinates activated NOTCH1, promoting its nuclear import, thereby acting as a positive regulator of Notch signaling. .

Protein sequence and domain

Belongs to the eIF-3 subunit F family. The MPN domain mediates deubiquitinating activity.

Protein post-translational modifications

Phosphorylation is enhanced upon serum stimulation. Phosphorylated during apoptosis by caspase-processed CDK11. .

Protein cellular localization

Cytoplasm .

Research area

All research areas>Signaling Intermediates>eIF
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

Reviews


There are no reviews yet.

Only logged in customers who have purchased this product may leave a review

There are no reviews for this product yet.
By submitting a review, get following benefits:

1. Receive $50 ABcoins as credit for each review.
2. First trial sample order will be fully refunded as credit.
3. Have a chance to win a $50 amazon gift card!

view database submit reviews

There is no extra validation for this product yet.
Check other extra validated antibodies below:



Welcome to AntibodyPlus!