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Rabbit Anti-EIF3H Antibody (CSB-PA007537ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Eukaryotic translation initiation factor 3 subunit 3 Antibody,eIF-3-gamma Antibody,eIF3 p40 subunit Antibody,EIF3H Antibody,EIF3S3 AntibodyMore alternative names for the antibody
eIF-3-gamma antibody|eIF3 gamma antibody|eIF3 p40 antibody|eIF3 p40 subunit antibody|eIF3h antibody|EIF3H_HUMAN antibody|EIF3S3 antibody|Eukaryotic translation initiation factor 3 subunit 3 antibody|Eukaryotic translation initiation factor 3 subunit H antibody|MGC102958 antibody
Anti-EIF3S3 antibody (ab60942)
Anti-EIF3S3 antibody (ab60942)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Eukaryotic translation initiation factor 3 subunit H protein (80-340AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:506873( Cow), Entrez Gene:8667( Human), Entrez Gene:68135( Mouse), Entrez Gene:100911110( Rat), Entrez Gene:299899( Rat), Omim:603912( Human), SwissProt:Q56JZ5( Cow), SwissProt:O15372( Human), SwissProt:Q91WK2( Mouse), SwissProt:Q6P9U8( Rat), Unigene:492599( Human), Unigene:289800( Mouse), Unigene:129213( Rat)
|Protein function|| |
Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). .
|Protein sequence and domain|| |
Belongs to the eIF-3 subunit H family.
|Protein cellular localization|| |
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|Product type|| |
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