Anti-EIF3K Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC,IP
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-EIF3K Antibody (CSB-PA866204ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Eukaryotic translation initiation factor 3 subunit K Antibody,Eukaryotic translation initiation factor 3 subunit 12 Antibody,EIF3K Antibody

More alternative names for the antibody
ARG134 antibody|eIF 3 p25 antibody|eIF 3 p28 antibody|eIF-3 p25 antibody|eIF-3 p28 antibody|EIF3-p28 antibody|eif3k antibody|EIF3K_HUMAN antibody|EIF3S12 antibody|Eukaryotic translation initiation factor 3 subunit 12 antibody|Eukaryotic translation initiation factor 3 subunit K antibody|HSPC029 antibody|M9 antibody|MSTP001 antibody|Muscle specific gene M9 protein antibody|Muscle-specific gene M9 protein antibody|PLAC 24 antibody|PLAC-24 antibody|PLAC24 antibody|PRO1474 antibody|PTD001 antibody
Anti-eIF3K antibody (ab26937)
Close sc-81262|sc-393234|sc-367760|sc-79476|

Recommended applications: ELISA, WB, IHC, IP

Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Recommended protocols: check protocols

Name

Anti-EIF3K Antibody

Catalogue No.

CSB-PA866204ESR1HU

Reactivity

Human

Immunogen

Recombinant human Eukaryotic translation initiation factor 3 subunit K protein (1-218AA)

Host

Rabbit

Applications

ELISA, WB, IHC, IP

Recommended dilution

Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

25 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:515326( Cow), Entrez Gene:27335( Human), Entrez Gene:73830( Mouse), Entrez Gene:444341( Xenopus laevis), Entrez Gene:550245( Zebrafish), Omim:609596( Human), SwissProt:Q3T0V3( Cow), SwissProt:Q9UBQ5( Human), SwissProt:Q9DBZ5( Mouse), SwissProt:Q6GNI4( Xenopus laevis), SwissProt:Q567V6( Zebrafish), Unigene:314359( Human), Unigene:29714( Mouse), Unigene:6031( Xenopus laevis), Unigene:104593( Zebrafish)

Protein function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). .

Protein tissue specificity

Ubiquitous, with the highest levels of expression in brain, testis and kidney. .

Protein sequence and domain

Belongs to the eIF-3 subunit K family.

Protein cellular localization

Nucleus . Cytoplasm .

Research area

All research areas>Signaling Intermediates>eIF
(View all antibody categories related to Signaling Intermediates)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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