Anti-EIF3M Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC,IP
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-EIF3M Antibody (CSB-PA745333DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Eukaryotic translation initiation factor 3 subunit M Antibody,Fetal lung protein B5 Antibody,hFL-B5 Antibody,PCI domain-containing protein 1 Antibody,EIF3M Antibody

More alternative names for the antibody
B5 antibody|B5 receptor antibody|Dendritic cell protein antibody|eIF3m antibody|EIF3M_HUMAN antibody|Eukaryotic translation initiation factor 3 subunit M antibody|Fetal lung protein B5 antibody|FLJ29030 antibody|GA17 antibody|hfl B5 antibody|hFL-B5 antibody|PCI domain containing 1 (herpesvirus entry mediator) antibody|PCI domain-containing protein 1 antibody|PCID1 antibody|TANGO7 antibody
Anti-PCID1 antibody (ab40829)
Close sc-133541|

Recommended applications: ELISA, WB, IHC, IP

Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Recommended protocols: check protocols

Name

Anti-EIF3M Antibody

Catalogue No.

CSB-PA745333DSR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Eukaryotic translation initiation factor 3 subunit M protein (1-374AA)

Host

Rabbit

Applications

ELISA, WB, IHC, IP

Recommended dilution

Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

42 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10480( Human), Entrez Gene:98221( Mouse), Entrez Gene:295975( Rat), GenBank:BC019103( Human), Omim:609641( Human), SwissProt:Q7L2H7( Human), SwissProt:Q99JX4( Mouse), Unigene:502244( Human), Unigene:379278( Mouse)

Protein function

Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17403899, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17403899). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773). .; (Microbial infection) May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). .

Protein tissue specificity

Broadly expressed. .

Protein sequence and domain

Belongs to the eIF-3 subunit M family.

Protein cellular localization

Cytoplasm .

Research area

All research areas>Signaling Intermediates>eIF
(View all antibody categories related to Signaling Intermediates)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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