Anti-ENPP2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ENPP2 Antibody (CSB-PA613427ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

E-NPP 2 Antibody,Autotaxin Antibody,Extracellular lysophospholipase D Antibody, LysoPLD Antibody,ENPP2 Antibody,ATX Antibody, PDNP2 Antibody

More alternative names for the antibody
ATX antibody|ATX X antibody|Autotaxin antibody|Autotaxin t antibody|E NPP 2 antibody|E-NPP 2 antibody|Ectonucleotide pyrophosphatase/phosphodiesterase 2 antibody|Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 antibody|Enpp2 antibody|ENPP2_HUMAN antibody|Extracellular lysophospholipase D antibody|FLJ26803 antibody|LysoPLD antibody|NPP2 antibody|PD IALPHA antibody|PDNP2 antibody|Phosphodiesterase I alpha antibody|Phosphodiesterase I/nucleotide pyrophosphatase 2 antibody|Plasma lysophospholipase D antibody
Anti-ENPP2 antibody (ab140915)
Close sc-374222|sc-66813|sc-33075|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ENPP2 Antibody

Catalogue No.

CSB-PA613427ESR1HU

Reactivity

Human

Immunogen

Recombinant human Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 protein (564-863AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

98 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:532663( Cow), Entrez Gene:5168( Human), Entrez Gene:18606( Mouse), Entrez Gene:84050( Rat), Omim:601060( Human), SwissProt:A1A4K5( Cow), SwissProt:Q13822( Human), SwissProt:Q9R1E6( Mouse), SwissProt:Q64610( Rat), Unigene:190977( Human), Unigene:250256( Mouse), Unigene:20403( Rat)

Protein function

Hydrolyzes lysophospholipids to produce lysophosphatidic acid (LPA) in extracellular fluids. Major substrate is lysophosphatidylcholine. Also can act on sphingosylphosphphorylcholine producing sphingosine-1-phosphate, a modulator of cell motility. Can hydrolyze, in vitro, bis-pNPP, to some extent pNP-TMP, and barely ATP. Involved in several motility-related processes such as angiogenesis and neurite outgrowth. Acts as an angiogenic factor by stimulating migration of smooth muscle cells and microtubule formation. Stimulates migration of melanoma cells, probably via a pertussis toxin-sensitive G protein. May have a role in induction of parturition. Possible involvement in cell proliferation and adipose tissue development. Tumor cell motility-stimulating factor. .

Protein tissue specificity

Predominantly expressed in brain, placenta, ovary, and small intestine. Expressed in a number of carcinomas such as hepatocellular and prostate carcinoma, neuroblastoma and non-small-cell lung cancer. Expressed in body fluids such as plasma, cerebral spinal fluid (CSF), saliva, follicular and amniotic fluids. Not detected in leukocytes. Isoform 1 is more highly expressed in peripheral tissues than in the central nervous system (CNS). Adipocytes only express isoform 1. Isoform 3 is more highly expressed in the brain than in peripheral tissues. .

Protein sequence and domain

Belongs to the nucleotide pyrophosphatase/phosphodiesterase family.

Protein post-translational modifications

N-glycosylation, but not furin-cleavage, plays a critical role on secretion and on lysoPLD activity. .

Protein cellular localization

Secreted . Note=Secreted by most body fluids including serum and CSF. Also by adipocytes and numerous cancer cells.

Research area

All research areas>Tumor Suppressor/Apoptosis>Autotaxin
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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