Anti-EPHB4 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-EPHB4 Antibody (CSB-PA007732ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Ephrin type-B receptor 4 Antibody,Hepatoma transmembrane kinase Antibody,Tyrosine-protein kinase TYRO11 Antibody,EPHB4 Antibody,HTK Antibody,MYK1 Antibody,TYRO11 Antibody

More alternative names for the antibody
CAPB antibody|EPH like kinase 2 antibody|EPH like kinase 6 antibody|EPH like tyrosine kinase 2 antibody|eph tyrosine kinase 2 antibody|eph tyrosine kinase 3 antibody|EPH-like kinase 6 antibody|Ephb1 antibody|EPHB1_HUMAN antibody|EPHB2 antibody|EPHB3 antibody|EPHB4 antibody|ephrin receptor EphB4 antibody|ephrin type B receptor 1 antibody|ephrin type B receptor 2 antibody|ephrin type B receptor 3 antibody|ephrin type B receptor 4 antibody|Ephrin type-B receptor 1 antibody|EPHT2 antibody|EPHT3 antibody|ERK antibody|ETK2 antibody|Hek 5 antibody|Hek 6 antibody|HEK2 antibody|HEK5 antibody|HEK6 antibody|hepatoma transmembrane kinase antibody|HTK antibody|human embryo kinase 2 antibody|MYK1 antibody|NET antibody|PCBC antibody|protein tyrosine kinase HEK5 antibody|renal carcinoma antigen NY REN 47 antibody|soluble EPHB1 variant 1 antibody|soluble EPHB4 variant 1 antibody|soluble EPHB4 variant 2 antibody|soluble EPHB4 variant 3 antibody|TYRO11 antibody|Tyro5 antibody|TYRO6 antibody|tyrosine protein kinase receptor EPH 2 antibody|tyrosine protein kinase receptor EPH 3 antibody|tyrosine protein kinase receptor EPH2 antibody|tyrosine protein kinase receptor EPH3 antibody|tyrosine protein kinase receptor HTK antibody|tyrosine protein kinase TYRO11 antibody|tyrosine protein kinase TYRO5 antibody|tyrosine protein kinase TYRO6 antibody|Tyrosine-protein kinase receptor EPH-2 antibody
Anti-Eph receptor B1 + Eph receptor B2 + Eph receptor B3 + Eph receptor B4 antibody (ab64820)
Close sc-130062|sc-130081|sc-7284|sc-5536|sc-7285|sc-130753|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-EPHB4 Antibody

Catalogue No.

CSB-PA007732ESR2HU

Reactivity

Human

Immunogen

Recombinant human Ephrin type-B receptor 4 protein (300-540AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

108 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:2047( Human), Entrez Gene:2048( Human), Entrez Gene:2049( Human), Entrez Gene:2050( Human), Entrez Gene:13844( Mouse), Entrez Gene:13845( Mouse), Entrez Gene:13846( Mouse), Entrez Gene:270190( Mouse), Omim:600011( Human), Omim:600600( Human), Omim:600997( Human), Omim:601839( Human), SwissProt:P29323( Human), SwissProt:P54760( Human), SwissProt:P54762( Human), SwissProt:P54754( Mouse), SwissProt:P54761( Mouse), SwissProt:P54763( Mouse), SwissProt:Q8CBF3( Mouse), Unigene:116092( Human), Unigene:2913( Human), Unigene:437008( Human), Unigene:523329( Human), Unigene:250981( Mouse), Unigene:3374( Mouse), Unigene:34533( Mouse), Unigene:6972( Mouse)

Protein function

Receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Together with its cognate ligand/functional ligand EFNB2 plays a central role in heart morphogenesis and angiogenesis through regulation of cell adhesion and cell migration. EPHB4-mediated forward signaling controls cellular repulsion and segregation form EFNB2-expressing cells. Plays also a role in postnatal blood vessel remodeling, morphogenesis and permeability and is thus important in the context of tumor angiogenesis. .

Protein tissue specificity

Abundantly expressed in placenta but also detected in kidney, liver, lung, pancreas, skeletal muscle and heart. Expressed in primitive and myeloid, but not lymphoid, hematopoietic cells. Also observed in cell lines derived from liver, breast, colon, lung, melanocyte and cervix. .

Protein sequence and domain

Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.

Protein post-translational modifications

Phosphorylated; autophosphorylation is stimulated by EFNB2.

Protein cellular localization

Cell membrane ; Single-pass type I membrane protein .

Research area

All research areas>Membrane Receptors>Eph
(View all antibody categories related to Membrane Receptors)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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