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Rabbit Anti-EPPIN Antibody (CSB-PA022583ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Eppin Antibody,Cancer/testis antigen 71 Antibody,CT71 Antibody,Epididymal protease inhibitor Antibody,Protease inhibitor WAP7 Antibody,Serine protease inhibitor-like with Kunitz and WAP domains 1 Antibody,WAP four-disulfide core domain protein 7 Antibody,EPPIN Antibody,SPINLW1 Antibody,WAP7 Antibody,WFDC7 AntibodyMore alternative names for the antibody
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Eppin protein (22-133AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility. .
|Protein tissue specificity|| |
In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells. .
|Protein sequence and domain|| |
The BPTI/Kunitz inhibitor domain is required for elastase inhibitory activity. BPTI/Kunitz inhibitor and WAP domains are involved in the protein antibacterial activity.
|Protein cellular localization|| |
Isoform 1: Secreted. Cell surface. Note=Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa.
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CUSABIO BIOTECH CO.
|Product type|| |
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