Anti-EPPIN Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-EPPIN Antibody (CSB-PA022583ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Eppin Antibody,Cancer/testis antigen 71 Antibody,CT71 Antibody,Epididymal protease inhibitor Antibody,Protease inhibitor WAP7 Antibody,Serine protease inhibitor-like with Kunitz and WAP domains 1 Antibody,WAP four-disulfide core domain protein 7 Antibody,EPPIN Antibody,SPINLW1 Antibody,WAP7 Antibody,WFDC7 Antibody

More alternative names for the antibody

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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-EPPIN Antibody

Catalogue No.

CSB-PA022583ESR1HU

Reactivity

Human

Immunogen

Recombinant human Eppin protein (22-133AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

15 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Protein function

Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility. .

Protein tissue specificity

In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells. .

Protein sequence and domain

The BPTI/Kunitz inhibitor domain is required for elastase inhibitory activity. BPTI/Kunitz inhibitor and WAP domains are involved in the protein antibacterial activity.

Protein cellular localization

Isoform 1: Secreted. Cell surface. Note=Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa.

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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