Anti-ERBIN Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-ERBIN Antibody (CSB-PA857021ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Protein LAP2 Antibody,Densin-180-like protein Antibody,Erbb2-interacting protein Antibody,Erbin Antibody,ERBB2IP Antibody,ERBIN Antibody,KIAA1225 Antibody,LAP2 Antibody

More alternative names for the antibody
Densin-180-like protein antibody|Erbb2-interacting protein antibody|Erbb2ip antibody|Erbin antibody|LAP2 antibody|LAP2_HUMAN antibody|Protein LAP2 antibody
Anti-Erbin antibody (ab55930)
Close sc-293468|sc-30054|sc-13249|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-ERBIN Antibody

Catalogue No.

CSB-PA857021ESR2HU

Reactivity

Human

Immunogen

Recombinant human Protein LAP2 protein (1193-1412AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

158 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:55914( Human), Entrez Gene:59079( Mouse), Omim:606944( Human), SwissProt:Q96RT1( Human), SwissProt:Q80TH2( Mouse), Unigene:519346( Human), Unigene:591774( Human), Unigene:597241( Human), Unigene:277354( Mouse)

Protein function

Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated ‘Tyr-1248’ of receptor ERBB2, it may contribute to stabilize this unphosphorylated state (PubMed:16203728). Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728). .

Protein tissue specificity

Highly expressed in brain, heart, kidney, muscle and stomach, followed by liver, spleen and intestine. .

Protein sequence and domain

Belongs to the LAP (LRR and PDZ) protein family.

Protein cellular localization

Cell junction, hemidesmosome . Nucleus membrane . Basolateral cell membrane . Note=Found in hemidesmosomes, which are cell-substrate adhesion complexes in stratified epithelia. In transfected cells, either diffusely distributed over the cytoplasm or concentrated at the basolateral membrane. Colocalizes with the adrenergic receptors, ADREN1A and ADREN1B, at the nuclear membrane of cardiac myocytes (By similarity). .

Research area

All research areas>Signaling Intermediates>ERBIN
(View all antibody categories related to Signaling Intermediates)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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