Anti-EZH1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-EZH1 Antibody (CSB-PA852913DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

ENX-2 Antibody,Enhancer of zeste homolog 1 Antibody,EZH1 Antibody,KIAA0388 Antibody

More alternative names for the antibody
Enhancer of zeste homolog 1 (Drosophila) antibody|Enhancer of zeste homolog 1 antibody|ENX-2 antibody|ENX2 antibody|Ezh1 antibody|EZH1_HUMAN antibody|Histone-lysine N-methyltransferase EZH1 antibody
Anti-EZH1 antibody (ab13665)
Close sc-20349|sc-292275|sc-20347|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-EZH1 Antibody

Catalogue No.

CSB-PA852913DSR1HU

Reactivity

Human

Immunogen

Recombinant human Histone-lysine N-methyltransferase EZH1 protein (160-280AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

85 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:2145( Human), Entrez Gene:14055( Mouse), Omim:601674 ( Human), SwissProt:Q92800( Human), SwissProt:P70351( Mouse), Unigene:194669( Human), Unigene:5027( Mouse)

Protein function

Polycomb group (PcG) protein. Catalytic subunit of the PRC2/EED-EZH1 complex, which methylates ‘Lys-27’ of histone H3, leading to transcriptional repression of the affected target gene. Able to mono-, di- and trimethylate ‘Lys-27’ of histone H3 to form H3K27me1, H3K27me2 and H3K27me3, respectively. Required for embryonic stem cell derivation and self-renewal, suggesting that it is involved in safeguarding embryonic stem cell identity. Compared to EZH2-containing complexes, it is less abundant in embryonic stem cells, has weak methyltransferase activity and plays a less critical role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. .

Protein sequence and domain

Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. EZ subfamily.

Protein cellular localization

Nucleus . Note=Colocalizes with trimethylated ‘Lys-27’ of histone H3.

Research area

All research areas>Transcription Regulators>ENX
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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