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Rabbit Anti-FABP6 Antibody (CSB-PA007955ESR1HU)
Supplier: CUSABIO BIOTECH CO.
GT Antibody,Fatty acid-binding protein 6 Antibody,Ileal lipid-binding protein Antibody,ILBP Antibody,Intestinal 15 kDa protein Antibody,I-15P Antibody,Intestinal bile acid-binding protein Antibody,I-BABP Antibody,FABP6 Antibody,ILBP Antibody, ILLBP AntibodyMore alternative names for the antibody
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Gastrotropin protein (1-128AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). .; Isoform 2: Essential for the survival of colon cancer cells to bile acid-induced apoptosis. .
|Protein tissue specificity|| |
Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). .
|Protein sequence and domain|| |
Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Can bind at least two ligands per molecule, however, the stoichiometry is debated.
|Protein cellular localization|| |
Isoform 1: Cytoplasm . Membrane; Peripheral membrane protein ; Cytoplasmic side .; Isoform 2: Cytoplasm . Note=Localized close to nucleus on the apical side of both normal and neoplastic cells. .
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CUSABIO BIOTECH CO.
|Product type|| |
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