Anti-FABP6 Antibody

$99.00$319.00

Reactivity: Human,Mouse,Rat
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-FABP6 Antibody (CSB-PA007955ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

GT Antibody,Fatty acid-binding protein 6 Antibody,Ileal lipid-binding protein Antibody,ILBP Antibody,Intestinal 15 kDa protein Antibody,I-15P Antibody,Intestinal bile acid-binding protein Antibody,I-BABP Antibody,FABP6 Antibody,ILBP Antibody, ILLBP Antibody

More alternative names for the antibody

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Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-FABP6 Antibody

Catalogue No.

CSB-PA007955ESR2HU

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant human Gastrotropin protein (1-128AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

14 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Protein function

Binds to bile acids and is involved in enterohepatic bile acid metabolism. Required for efficient apical to basolateral transport of conjugated bile acids in ileal enterocytes (By similarity). In vitro binds to bile acids in the order: deoxycholic acid > cholic acid > chenodeoxycholic acid and respective BA conjugation modifies affinities in the order taurine-conjugated > glycine-conjugated > unconjugated bile acids. Stimulates gastric acid and pepsinogen secretion (By similarity). .; Isoform 2: Essential for the survival of colon cancer cells to bile acid-induced apoptosis. .

Protein tissue specificity

Isoform 1 is expressed in the jejunum, ileum, cecum and ascending colon intestine. Isoform 2 is xpressed in the gallbladder, duodenum, jejunum, ileum, cecum, ascending, transverse and descending colon, sigmoid colon and rectum. Isoform 2 is expressed in colorectal adenocarcinomas and their adjacent normal mucosa (at protein level). .

Protein sequence and domain

Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. Forms a beta-barrel structure that accommodates the hydrophobic ligand in its interior. Can bind at least two ligands per molecule, however, the stoichiometry is debated.

Protein cellular localization

Isoform 1: Cytoplasm . Membrane; Peripheral membrane protein ; Cytoplasmic side .; Isoform 2: Cytoplasm . Note=Localized close to nucleus on the apical side of both normal and neoplastic cells. .

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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