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Rabbit Anti-FAM20A Antibody (CSB-PA850394ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Pseudokinase FAM20ACurated Antibody,FAM20A AntibodyMore alternative names for the antibody
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Pseudokinase FAM20A protein (140-240AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Protein function|| |
Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the ‘matrix’ that guides the deposition of the enamel minerals. .
|Protein tissue specificity|| |
Highly expressed in lung and liver. Intermediate levels in thymus and ovary. .
|Involvement in disease|| |
Amelogenesis imperfecta 1G (AI1G) [MIM:204690]: A disorder characterized by dental anomalies, gingival overgrowth, and nephrocalcinosis. Dental anomalies include hypoplastic amelogenesis imperfecta, intrapulpal calcifications, delay of tooth eruption, hypodontia/oligodontia, pericoronal radiolucencies and unerupted teeth. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the FAM20 family.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Secreted . Golgi apparatus . Endoplasmic reticulum .
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CUSABIO BIOTECH CO.
|Product type|| |
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