Anti-FBP1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-FBP1 Antibody (CSB-PA008459ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Fructose-1 Antibody,6-bisphosphatase 1 Antibody,FBPase 1 Antibody,D-fructose-1 Antibody,6-bisphosphate 1-phosphohydrolase 1 Antibody,Liver FBPase Antibody,FBP1 Antibody,FBP Antibody

More alternative names for the antibody
6-bisphosphatase 1 antibody|6-bisphosphate 1-phosphohydrolase 1 antibody|D fructose 1 6 bisphosphate 1 phosphohydrolase 1 antibody|D-fructose-1 antibody|EC 3.1.3.11 antibody|F16P1_HUMAN antibody|FBP antibody|FBP 1 antibody|FBP1 antibody|FBPase 1 antibody|Fructose 1 6 bisphosphatase 1 antibody|Fructose bisphosphatase 1 antibody|Fructose-1 antibody|Growth inhibiting protein 17 antibody|Liver fructose bisphosphatase antibody
Anti-FBP1 antibody [EPR4619] (ab109020)
Close sc-32433|sc-32435|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-FBP1 Antibody

Catalogue No.

CSB-PA008459ESR2HU

Reactivity

Human

Immunogen

Recombinant human Fructose-1,6-bisphosphatase 1 protein (1-338AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

36 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:2203( Human), Entrez Gene:14121( Mouse), Entrez Gene:24362( Rat), Omim:611570( Human), SwissProt:P09467( Human), SwissProt:Q9QXD6( Mouse), SwissProt:P19112( Rat), Unigene:494496( Human), Unigene:423078( Mouse), Unigene:33703( Rat)

Protein function

Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations, acting as a rate-limiting enzyme in gluconeogenesis. Plays a role in regulating glucose sensing and insulin secretion of pancreatic beta-cells. Appears to modulate glycerol gluconeogenesis in liver. Important regulator of appetite and adiposity; increased expression of the protein in liver after nutrient excess increases circulating satiety hormones and reduces appetite-stimulating neuropeptides and thus seems to provide a feedback mechanism to limit weight gain. .

Protein tissue specificity

Expressed in pancreatic islets. .

Involvement in disease

Fructose-1,6-bisphosphatase deficiency (FBP1D) [MIM:229700]: An autosomal recessive metabolic disorder characterized by impaired gluconeogenesis, and episodes of hypoglycemia and metabolic acidosis that can be lethal in newborn infants or young children. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the FBPase class 1 family.

Research area

All research areas>Synthesis and Degradation>liver FBPase
(View all antibody categories related to Synthesis and Degradation)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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