Anti-FBXO6 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-FBXO6 Antibody (CSB-PA873634ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

F-box only protein 6 Antibody,F-box protein that recognizes sugar chains 2 Antibody,F-box/G-domain protein 2 Antibody,FBXO6 Antibody,FBG2 Antibody,FBS2 Antibody,FBX6 Antibody

More alternative names for the antibody
F box protein that recognizes sugar chains 2 antibody|F box G domain protein 2 antibody|F box only protein 6 antibody|F box protein 6 antibody|F box protein FBG2 antibody|F box protein Fbx6 antibody|F box/G domain protein 2 antibody|F-box only protein 6 antibody|F-box protein that recognizes sugar chains 2 antibody|F-box/G-domain protein 2 antibody|FBG 2 antibody|FBG2 antibody|FBS 2 antibody|FBS2 antibody|FBX 6 antibody|FBX6 antibody|FBX6_HUMAN antibody|FBXO 6 antibody|FBXO6 antibody|OTTHUMP00000002267 antibody
Anti-FbxO6 antibody (ab153853)
Close sc-134339|sc-99108|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-FBXO6 Antibody

Catalogue No.

CSB-PA873634ESR1HU

Reactivity

Human

Immunogen

Recombinant human F-box only protein 6 protein (104-293AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

33 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:26270( Human), Omim:605647( Human), SwissProt:Q9NRD1( Human), Unigene:464419( Human)

Protein function

Substrate-recognition component of some SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes. Involved in endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranlocated into the cytosol and promoting their ubiquitination and subsequent degradation. Able to recognize and bind denatured glycoproteins, which are modified with not only high-mannose but also complex-type oligosaccharides. Also recognizes sulfated glycans. Also involved in DNA damage response by specifically recognizing activated CHEK1 (phosphorylated on ‘Ser-345’), promoting its ubiquitination and degradation. Ubiquitination of CHEK1 is required to insure that activated CHEK1 does not accumulate as cells progress through S phase, or when replication forks encounter transient impediments during normal DNA replication. .

Protein cellular localization

Cytoplasm .

Research area

All research areas>Signaling Intermediates>FBXO
(View all antibody categories related to Signaling Intermediates)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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