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Rabbit Anti-FBXW4 Antibody (CSB-PA008525ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Dactylin Antibody,F-box and WD-40 domain-containing protein 4 Antibody,FBXW4 Antibody,FBW4 Antibody,SHFM3 AntibodyMore alternative names for the antibody
DAC antibody|Dactylin antibody|F box and WD 40 domain containing protein 4 antibody|F box and WD 40 domain protein 4 antibody|F box and WD repeat domain containing 4 antibody|F box/WD repeat containing protein 4 antibody|F box/WD repeat protein 4 antibody|F-box and WD-40 domain-containing protein 4 antibody|F-box/WD repeat-containing protein 4 antibody|FBW 4 antibody|FBW4 antibody|FBWD 4 antibody|FBWD4 antibody|FBXW 4 antibody|FBXW4 antibody|FBXW4_HUMAN antibody|OTTHUMP00000059175 antibody|SHFM 3 antibody|SHSF 3 antibody|SHSF3 antibody|Split hand/foot malformation (ectrodactyly) type antibody
Anti-SHFM3 antibody (ab60116)
Anti-SHFM3 antibody (ab60116)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human F-box/WD repeat-containing protein 4 protein (143-412AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=6468" target="_blank">Entrez Gene:6468( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/608071" target="_blank">Omim:608071( Human)</a>, <a href="http://www.uniprot.org/uniprot/P57775" target="_blank">SwissProt:P57775( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=500822" target="_blank">Unigene:500822( Human)</a>
|Protein function|| |
Probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. Likely to be involved in key signaling pathways crucial for normal limb development. May participate in Wnt signaling.
|Protein tissue specificity|| |
Expressed in brain, kidney, lung and liver.
|Involvement in disease|| |
Split-hand/foot malformation 3 (SHFM3) [MIM:246560]: A limb malformation involving the central rays of the autopod and presenting with syndactyly, median clefts of the hands and feet, and aplasia and/or hypoplasia of the phalanges, metacarpals, and metatarsals. Some patients have been found to have mental retardation, ectodermal and craniofacial findings, and orofacial clefting. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Signaling-Intermediates/">Signaling Intermediates</a>><a href="https://antibodyplus.com/product-tag/SHFM/">SHFM</a><br><a href="https://antibodyplus.com/product-tag/Signaling-Intermediates/"> (View all antibody categories related to Signaling Intermediates)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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