Anti-FCMR Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-FCMR Antibody (CSB-PA007972ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Regulator of Fas-induced apoptosis Toso Antibody,FAIM3 Antibody,TOSO Antibody

More alternative names for the antibody
Faim3 antibody|FAIM3_HUMAN antibody|Fas apoptotic inhibitory molecule 3 antibody|Fc fragment of IgM receptor antibody|Fc mu receptor antibody|FCMR antibody|IgM Fc receptor antibody|Immunoglobulin mu Fc receptor antibody|Regulator of Fas induced apoptosis antibody|Regulator of Fas-induced apoptosis Toso antibody|TOSO antibody
Anti-FAIM3 antibody (ab56487)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-FCMR Antibody

Catalogue No.

CSB-PA007972ESR2HU

Reactivity

Human

Immunogen

Recombinant human Fas apoptotic inhibitory molecule 3 protein (18-251AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

43 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:9214( Human), Omim:606015( Human), SwissProt:O60667( Human), Unigene:58831( Human), Unigene:728324( Human)

Protein function

May play a role in the immune system processes. Protects cells from FAS-, TNF alpha- and FADD-induced apoptosis without increasing expression of the inhibitors of apoptosis BCL2 and BCLXL. Seems to activate an inhibitory pathway that prevents CASP8 activation following FAS stimulation, rather than blocking apoptotic signals downstream. May inhibit FAS-induced apoptosis by preventing CASP8 processing through CFLAR up-regulation. .

Protein tissue specificity

Expressed in lymph nodes, peripheral blood leukocytes, lung, thymus and kidneys. Very weak expression detected in spleen, liver, heart, and salivary gland. Expressed in lymphoid cell lines such as Jurkat, CEM-T4, MOLT-4, HB11;19 and Reh. No expression detected in nonhematopoietic cell lines including Hep-G2, HEK293 and HeLa. Detected at high levels in chronic lymphocytic leukemia cells. .

Protein sequence and domain

The Ig-like domain is required for the anti-apoptotic ability.

Protein cellular localization

Isoform 1: Membrane ; Single-pass membrane protein .; Isoform 3: Secreted . Note=Detected in the serum. .

Research area

All research areas>Tumor Suppressor/Apoptosis>Toso
(View all antibody categories related to Tumor Suppressor/Apoptosis)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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