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Rabbit Anti-FOXP2 Antibody (CSB-PA008842DSR1HU)
Supplier: CUSABIO BIOTECH CO.
CAG repeat protein 44 Antibody,Trinucleotide repeat-containing gene 10 protein Antibody,FOXP2 Antibody,CAGH44 Antibody, TNRC10 AntibodyMore alternative names for the antibody
CAG repeat protein 44 antibody|CAGH44 antibody|DKFZp686H1726 antibody|Forkhead box P2 antibody|Forkhead box protein P2 antibody|forkhead/winged-helix transcription factor antibody|FOX P2 antibody|FOXP2 antibody|FOXP2_HUMAN antibody|HGNC11222 antibody|HGNC11956 antibody|SPCH 1 antibody|SPCH1 antibody|TNRC 10 antibody|TNRC10 antibody|trinucleotide repeat containing 10 antibody|Trinucleotide repeat containing gene 10 protein antibody|Trinucleotide repeat-containing gene 10 protein antibody
Anti-FOXP2 antibody (ab16046)
Anti-FOXP2 antibody (ab16046)
Recommended applications: ELISA, IHC
Recommended dilution: Recommended dilution:IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Forkhead box protein P2 protein (416-715AA)
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=93986" target="_blank">Entrez Gene:93986( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=114142" target="_blank">Entrez Gene:114142( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=500037" target="_blank">Entrez Gene:500037( Rat)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/605317" target="_blank">Omim:605317( Human)</a>, <a href="http://www.uniprot.org/uniprot/O15409" target="_blank">SwissProt:O15409( Human)</a>, <a href="http://www.uniprot.org/uniprot/P58463" target="_blank">SwissProt:P58463( Mouse)</a>, <a href="http://www.uniprot.org/uniprot/P0CF24" target="_blank">SwissProt:P0CF24( Rat)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=282787" target="_blank">Unigene:282787( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=332919" target="_blank">Unigene:332919( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=225249" target="_blank">Unigene:225249( Rat)</a>
|Protein function|| |
Transcriptional repressor that may play a role in the specification and differentiation of lung epithelium. May also play a role in developing neural, gastrointestinal and cardiovascular tissues. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Plays a role in synapse formation by regulating SRPX2 levels. Involved in neural mechanisms mediating the development of speech and language.
|Protein tissue specificity|| |
Isoform 1 and isoform 6 are expressed in adult and fetal brain, caudate nucleus and lung. .
|Involvement in disease|| |
Speech-language disorder 1 (SPCH1) [MIM:602081]: A disorder characterized by severe orofacial dyspraxia resulting in largely incomprehensible speech. Affected individuals have severe impairment in the selection and sequencing of fine orofacial movements which are necessary for articulation, and deficits in several facets of grammatical skills and language processing, such as the ability to break up words into their constituent phonemes. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Note=A chromosomal aberration involving FOXP2 is a cause of severe speech and language impairment. Translocation t(5;7)(q22;q31.2).
|Protein sequence and domain|| |
The leucine-zipper is required for dimerization and transcriptional repression.
|Protein cellular localization|| |
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Transcription-Regulators/">Transcription Regulators</a>><a href="https://antibodyplus.com/product-tag/FOX/">FOX</a><br><a href="https://antibodyplus.com/product-tag/Transcription-Regulators/"> (View all antibody categories related to Transcription Regulators)</a>
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|Product type|| |
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