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Rabbit Anti-GATA2 Antibody (CSB-PA340572ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Endothelial transcription factor GATA-2 Antibody,GATA-binding protein 2 Antibody,GATA2 AntibodyMore alternative names for the antibody
DCML antibody|Endothelial transcription factor GATA 2 antibody|Endothelial transcription factor GATA-2 antibody|Endothelial transcription factor GATA2 antibody|FLJ45948 antibody|GATA 2 antibody|GATA binding protein 2 antibody|GATA-binding protein 2 antibody|Gata2 antibody|GATA2_HUMAN antibody|IMD21 antibody|MGC2306 antibody|MONOMAC antibody|NFE 1B antibody|NFE1B antibody|OTTHUMP00000216240 antibody
Anti-GATA2 antibody – ChIP Grade (ab22849)
Anti-GATA2 antibody – ChIP Grade (ab22849)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Endothelial transcription factor GATA-2 protein (1-300AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:416018( Chicken), Entrez Gene:2624( Human), Entrez Gene:14461( Mouse), Entrez Gene:25159( Rat), Omim:137295( Human), SwissProt:P23824( Chicken), SwissProt:P23769( Human), SwissProt:O09100( Mouse), SwissProt:Q924Y4( Rat), Unigene:367725( Human), Unigene:34322( Rat)
|Protein function|| |
Transcriptional activator which regulates endothelin-1 gene expression in endothelial cells. Binds to the consensus sequence 5′-AGATAG-3′.
|Protein tissue specificity|| |
|Involvement in disease|| |
Immunodeficiency 21 (IMD21) [MIM:614172]: An immunodeficiency disease characterized by profoundly decreased or absent monocytes, B-lymphocytes, natural killer lymphocytes, and circulating and tissue dendritic cells, with little or no effect on T-cell numbers. Clinical features of DCML include susceptibility to disseminated non-tuberculous mycobacterial infections, papillomavirus infections, opportunistic fungal infections, and pulmonary alveolar proteinosis. Bone marrow hypocellularity and dysplasia of myeloid, erythroid, and megakaryocytic lineages are present in most patients, as are karyotypic abnormalities, including monosomy 7 and trisomy 8. This syndrome links susceptibility to mycobacterial, viral, and fungal infections with malignancy and can be transmitted in an autosomal dominant pattern. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Lymphedema, primary, with myelodysplasia (LMPM) [MIM:614038]: A chronic disabling condition characterized by swelling of the extremities due to altered lymphatic flow, associated with myelodysplasia. Patients with lymphedema suffer from recurrent local infections, and physical impairment. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Myelodysplastic syndrome (MDS) [MIM:614286]: A heterogeneous group of closely related clonal hematopoietic disorders. All are characterized by a hypercellular or hypocellular bone marrow with impaired morphology and maturation, dysplasia of the myeloid, megakaryocytic and/or erythroid lineages, and peripheral blood cytopenias resulting from ineffective blood cell production. Included diseases are: refractory anemia (RA), refractory anemia with ringed sideroblasts (RARS), refractory anemia with excess blasts (RAEB), refractory cytopenia with multilineage dysplasia and ringed sideroblasts (RCMD-RS); chronic myelomonocytic leukemia (CMML) is a myelodysplastic/myeloproliferative disease. MDS is considered a premalignant condition in a subgroup of patients that often progresses to acute myeloid leukemia (AML). . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein cellular localization|| |
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|Product type|| |
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