Anti-GATA3 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-GATA3 Antibody (CSB-PA009276ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

GATA-binding factor 3 Antibody,GATA3 Antibody

More alternative names for the antibody
DCML antibody|Endothelial transcription factor GATA 2 antibody|GATA binding factor 3 antibody|GATA binding protein 2 antibody|GATA binding protein 3 antibody|HDR antibody|HDRS antibody|IMD21 antibody|MONOMAC antibody|NFE1B antibody|Trans acting T cell specific transcription factor GATA 3 antibody
Anti-GATA2 antibody – ChIP Grade (ab22849)
Close sc-267|sc-16044|sc-9008|sc-515178|sc-1235|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-GATA3 Antibody

Catalogue No.

CSB-PA009276ESR2HU

Reactivity

Human

Immunogen

Recombinant human Trans-acting T-cell-specific transcription factor GATA-3 protein (1-260AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-2000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

47 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:416018( Chicken), Entrez Gene:2624( Human), Entrez Gene:14461( Mouse), Entrez Gene:25159( Rat), Omim:137295( Human), SwissProt:P23824( Chicken), SwissProt:P23769( Human), SwissProt:O09100( Mouse), SwissProt:Q924Y4( Rat), Unigene:367725( Human), Unigene:34322( Rat)

Protein function

Transcriptional activator which binds to the enhancer of the T-cell receptor alpha and delta genes. Binds to the consensus sequence 5′-AGATAG-3′. Required for the T-helper 2 (Th2) differentiation process following immune and inflammatory responses. .

Protein tissue specificity

T-cells and endothelial cells.

Involvement in disease

Hypoparathyroidism, sensorineural deafness, and renal disease (HDR) [MIM:146255]: A disease characterized by steroid-resistant nephrosis with progressive renal failure, hypoparathyroidism, sensorineural deafness, and renal dysplasia. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Binds DNA via the 2 GATA-type zinc fingers. Each zinc finger may bind either adjacent sites in a palindromic motif, or a different DNA molecule allowing looping and long-range gene regulation.; The YxKxHxxxRP motif is critical for DNA-binding and function.

Protein cellular localization

Nucleus.

Research area

All research areas>Transcription Regulators>GATA
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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