Anti-GATM Antibody

$99.00$319.00

Reactivity: Human,Mouse
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-GATM Antibody (CSB-PA009284ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

L-arginine:glycine amidinotransferase Antibody,Transamidinase Antibody,GATM Antibody,AGAT Antibody

More alternative names for the antibody
AGAT antibody|AT antibody|GATM antibody|GATM_HUMAN antibody|Glycine amidinotransferase antibody|Glycine amidinotransferase, mitochondrial antibody|L-arginine:glycine amidinotransferase antibody|mitochondrial antibody|Transamidinase antibody
Anti-GATM antibody (ab87062)
Close sc-241785|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-GATM Antibody

Catalogue No.

CSB-PA009284ESR1HU

Reactivity

Human, Mouse

Immunogen

Recombinant human Glycine amidinotransferase, mitochondrial protein (124-423AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:500-5000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

48 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:2628( Human), Entrez Gene:67092( Mouse), Entrez Gene:81660( Rat), Entrez Gene:266799( Zebrafish), Omim:602360( Human), SwissProt:P50440( Human), SwissProt:Q9D964( Mouse), SwissProt:P50442( Rat), SwissProt:Q6PH19( Zebrafish), Unigene:75335( Human), Unigene:29975( Mouse), Unigene:17661( Rat), Unigene:75520( Zebrafish)

Protein function

Catalyzes the biosynthesis of guanidinoacetate, the immediate precursor of creatine. Creatine plays a vital role in energy metabolism in muscle tissues. May play a role in embryonic and central nervous system development. May be involved in the response to heart failure by elevating local creatine synthesis. .

Protein tissue specificity

Expressed in brain, heart, kidney, liver, lung, salivary gland and skeletal muscle tissue, with the highest expression in kidney. Biallelically expressed in placenta and fetal tissues. .

Involvement in disease

Cerebral creatine deficiency syndrome 3 (CCDS3) [MIM:612718]: An autosomal recessive disorder characterized by developmental delay/regression, mental retardation, severe disturbance of expressive and cognitive speech, and severe depletion of creatine/phosphocreatine in the brain. Most patients develop a myopathy characterized by muscle weakness and atrophy later in life. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the amidinotransferase family. One chain folds into a compact single domain composed of repeating units, five beta-beta-alpha-beta modules, which surround the central active site.

Protein cellular localization

Isoform 1: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side. Note=Probably attached to the outer side of the inner membrane.; Isoform 2: Cytoplasm.

Research area

All research areas>Synthesis and Degradation>AGAT
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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