Anti-GGA2 Antibody

$99.00$319.00

Reactivity: Human,Mouse,Rat
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-GGA2 Antibody (CSB-PA891942ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Gamma-adaptin-related protein 2 Antibody,Golgi-localized Antibody, gamma ear-containing Antibody, ARF-binding protein 2 Antibody,VHS domain and ear domain of gamma-adaptin Antibody,Vear Antibody,GGA2 Antibody,KIAA1080 Antibody

More alternative names for the antibody
1200007E24Rik antibody|gamma ear-containing antibody|GGA 2 antibody|Gga2 antibody|GGA2_HUMAN antibody|Golgi associated gamma adaptin ear containing ARF binding protein 2 antibody|Golgi localized gamma ear containing ARF binding protein 2 antibody|Golgi-localized antibody|KIAA1080 antibody|Vear antibody|VHS domain and ear domain containing protein antibody|VHS domain and ear domain of gamma adaptin antibody|VHS domain and ear domain of gamma-adaptin antibody
Anti-GGA2 antibody (ab153928)
Close sc-135922|sc-133147|sc-30103|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-GGA2 Antibody

Catalogue No.

CSB-PA891942ESR1HU

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant human ADP-ribosylation factor-binding protein GGA2 protein (1-300AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

67 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:23062( Human), Entrez Gene:74105( Mouse), Entrez Gene:293455( Rat), Omim:606005( Human), SwissProt:Q9UJY4( Human), SwissProt:Q6P5E6( Mouse), Unigene:460336( Human), Unigene:29619( Mouse), Unigene:18248( Rat)

Protein function

Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.

Protein tissue specificity

Ubiquitously expressed.

Protein sequence and domain

Belongs to the GGA protein family. The VHS domain functions as a recognition module for sorting signals composed of an acidic cluster followed by two leucines (AC-LL motif).; The GAT domain is responsible for interaction with ARF-GTP, UBC and RABEP1. Required for recruitment to the TGN it prevents ARF-GTP hydrolysis.; The unstructured hinge region contains clathrin-binding but no autoinhibitory (AC-LL) motifs.; The GAE domain binds accessory proteins regulating GGAs function.

Protein post-translational modifications

Ubiquitinated. .

Protein cellular localization

Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein .

Research area

All research areas>Transport and Trafficking>GGA
(View all antibody categories related to Transport and Trafficking)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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