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Rabbit Anti-GGA2 Antibody (CSB-PA891942ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Gamma-adaptin-related protein 2 Antibody,Golgi-localized Antibody, gamma ear-containing Antibody, ARF-binding protein 2 Antibody,VHS domain and ear domain of gamma-adaptin Antibody,Vear Antibody,GGA2 Antibody,KIAA1080 AntibodyMore alternative names for the antibody
1200007E24Rik antibody|gamma ear-containing antibody|GGA 2 antibody|Gga2 antibody|GGA2_HUMAN antibody|Golgi associated gamma adaptin ear containing ARF binding protein 2 antibody|Golgi localized gamma ear containing ARF binding protein 2 antibody|Golgi-localized antibody|KIAA1080 antibody|Vear antibody|VHS domain and ear domain containing protein antibody|VHS domain and ear domain of gamma adaptin antibody|VHS domain and ear domain of gamma-adaptin antibody
Anti-GGA2 antibody (ab153928)
Anti-GGA2 antibody (ab153928)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Human, Mouse, Rat
Recombinant human ADP-ribosylation factor-binding protein GGA2 protein (1-300AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:23062( Human), Entrez Gene:74105( Mouse), Entrez Gene:293455( Rat), Omim:606005( Human), SwissProt:Q9UJY4( Human), SwissProt:Q6P5E6( Mouse), Unigene:460336( Human), Unigene:29619( Mouse), Unigene:18248( Rat)
|Protein function|| |
Plays a role in protein sorting and trafficking between the trans-Golgi network (TGN) and endosomes. Mediates the ARF-dependent recruitment of clathrin to the TGN and binds ubiquitinated proteins and membrane cargo molecules with a cytosolic acidic cluster-dileucine (AC-LL) motif.
|Protein tissue specificity|| |
|Protein sequence and domain|| |
Belongs to the GGA protein family. The VHS domain functions as a recognition module for sorting signals composed of an acidic cluster followed by two leucines (AC-LL motif).; The GAT domain is responsible for interaction with ARF-GTP, UBC and RABEP1. Required for recruitment to the TGN it prevents ARF-GTP hydrolysis.; The unstructured hinge region contains clathrin-binding but no autoinhibitory (AC-LL) motifs.; The GAE domain binds accessory proteins regulating GGAs function.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Golgi apparatus, trans-Golgi network membrane ; Peripheral membrane protein . Endosome membrane ; Peripheral membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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