Anti-GLO1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-GLO1 Antibody (CSB-PA871864DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Aldoketomutase Antibody,Glyoxalase I Antibody,Glx I Antibody,Ketone-aldehyde mutase Antibody,Methylglyoxalase Antibody,S-D-lactoylglutathione methylglyoxal lyase Antibody,GLO1 Antibody

More alternative names for the antibody
Aldoketomutase antibody|glo1 antibody|GLOD1 antibody|Glx I antibody|GLYI antibody|glyoxalase domain containing 1 antibody|Glyoxalase I antibody|Ketone aldehyde mutase antibody|Ketone-aldehyde mutase antibody|Lactoyl glutathione lyase antibody|Lactoylglutathione lyase antibody|LGUL_HUMAN antibody|Methylglyoxalase antibody|S D lactoylglutathione methylglyoxal lyase antibody|S-D-lactoylglutathione methylglyoxal lyase antibody
Anti-GLO1 antibody [6F10] (ab81461)
Close sc-101537|sc-133214|sc-133144|sc-67351|sc-133213|sc-101877|sc-271556|sc-50731|

Recommended applications: ELISA, WB, IHC

Recommended dilution: Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-GLO1 Antibody

Catalogue No.

CSB-PA871864DSR1HU

Reactivity

Human

Immunogen

Recombinant human Lactoylglutathione lyase protein (1-184AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

Recommended dilution:WB:1:200-1000,IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

20 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:2739( Human), Entrez Gene:109801( Mouse), Omim:138750( Human), SwissProt:Q04760( Human), SwissProt:Q9CPU0( Mouse), Unigene:268849( Human), Unigene:261984( Mouse)

Protein function

Catalyzes the conversion of hemimercaptal, formed from methylglyoxal and glutathione, to S-lactoylglutathione. Involved in the regulation of TNF-induced transcriptional activity of NF-kappa-B. Required for normal osteoclastogenesis. .

Protein sequence and domain

Belongs to the glyoxalase I family.

Protein post-translational modifications

Glutathionylation at Cys-139 inhibits enzyme activity. .; Phosphorylated at Thr-107 in the presence of CaMK2. However, this is a consensus site for phosphorylation by CK2 so phosphorylation may be mediated by CK2 rather than CaMK2. Phosphorylation is induced by TNF and suppresses the TNF-induced transcriptional activity of NF-kappa-B. .; Exists in a nitric oxide (NO)-modified form. The exact nature of the modification is unknown, but it suppresses the TNF-induced transcriptional activity of NF-kappa-B.

Research area

All research areas>Synthesis and Degradation>Glyoxalase
(View all antibody categories related to Synthesis and Degradation)

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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