Anti-GLRX2 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-GLRX2 Antibody (CSB-PA878876DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

GLRX2 Antibody,GRX2 Antibody,CGI-133 Antibody

More alternative names for the antibody
bA101E13.1 (GRX2 glutaredoxin (thioltransferase) 2) antibody|bA101E13.1 antibody|CGI133 antibody|Glrx2 antibody|GLRX2_HUMAN antibody|Glutaredoxin-2 antibody|Glutaredoxin-2, mitochondrial antibody|GRX2 antibody|mitochondrial antibody
Anti-Glutaredoxin 2 antibody – C-terminal (ab85267)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-GLRX2 Antibody

Catalogue No.

CSB-PA878876DSR1HU

Reactivity

Human

Immunogen

Recombinant human Glutaredoxin-2, mitochondrial protein (1-124AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

18 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:51022( Human), Entrez Gene:69367( Mouse), Omim:606820( Human), SwissProt:Q9NS18( Human), SwissProt:Q923X4( Mouse), Unigene:458283( Human), Unigene:272727( Mouse)

Protein function

Glutathione-dependent oxidoreductase that facilitates the maintenance of mitochondrial redox homeostasis upon induction of apoptosis by oxidative stress. Involved in response to hydrogen peroxide and regulation of apoptosis caused by oxidative stress. Acts as a very efficient catalyst of monothiol reactions because of its high affinity for protein glutathione-mixed disulfides. Can receive electrons not only from glutathione (GSH), but also from thioredoxin reductase supporting both monothiol and dithiol reactions. Efficiently catalyzes both glutathionylation and deglutathionylation of mitochondrial complex I, which in turn regulates the superoxide production by the complex. Overexpression decreases the susceptibility to apoptosis and prevents loss of cardiolipin and cytochrome c release. .

Protein tissue specificity

Widely expressed. Expressed in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, small intestine, placenta and lung. Not expressed in peripheral blood leukocytes. .

Protein sequence and domain

Belongs to the glutaredoxin family.

Protein cellular localization

Isoform 1: Mitochondrion.; Isoform 2: Nucleus.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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