Anti-GLRX3 Antibody

$99.00$319.00

Reactivity: Human,Rat
Applications: ELISA,WB,IHC,IP
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-GLRX3 Antibody (CSB-PA009523DSR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

PKC-interacting cousin of thioredoxin Antibody,PICOT Antibody,PKC-theta-interacting protein Antibody,PKCq-interacting protein Antibody,Thioredoxin-like protein 2 Antibody,GLRX3 Antibody,PICOT Antibody, TXNL2 Antibody,HUSSY-22 Antibody

More alternative names for the antibody
glrx3 antibody|GLRX3_HUMAN antibody|GLRX4 antibody|Glutaredoxin 3 antibody|Glutaredoxin 4 antibody|Glutaredoxin-3 antibody|GRX3 antibody|GRX4 antibody|PICOT antibody|PKC interacting cousin of thioredoxin antibody|PKC theta interacting protein antibody|PKC-interacting cousin of thioredoxin antibody|PKC-theta-interacting protein antibody|PKCq interacting protein antibody|PKCq-interacting protein antibody|Thioredoxin like protein 2 antibody|Thioredoxin-like protein 2 antibody|TXNL3 antibody
Anti-TXNL2 antibody – N-terminal (ab211298)
Close sc-390068|sc-100601|sc-69309|

Recommended applications: ELISA, WB, IHC, IP

Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Recommended protocols: check protocols

Name

Anti-GLRX3 Antibody

Catalogue No.

CSB-PA009523DSR1HU

Reactivity

Human, Rat

Immunogen

Recombinant human Glutaredoxin-3 protein (1-335AA)

Host

Rabbit

Applications

ELISA, WB, IHC, IP

Recommended dilution

Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

37 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:10539( Human), Entrez Gene:30926( Mouse), Omim:612754( Human), SwissProt:O76003( Human), SwissProt:Q9CQM9( Mouse), Unigene:42644( Human), Unigene:267692( Mouse)

Protein function

Together with BOLA2, acts as a cytosolic iron-sulfur (Fe-S) cluster assembly factor that facilitates [2Fe-2S] cluster insertion into a subset of cytosolic proteins (PubMed:26613676, PubMed:27519415). Acts as a critical negative regulator of cardiac hypertrophy and a positive inotropic regulator (By similarity). Required for hemoglobin maturation (PubMed:23615448). Does not posses any thyoredoxin activity since it lacks the conserved motif that is essential for catalytic activity. .

Protein tissue specificity

Expressed in heart, spleen, testis and, to a lower extent, in thymus and peripheral blood leukocytes. Weakly expressed in lung, placenta, colon and small intestine.

Protein sequence and domain

The thioredoxin domain lacks the two redox-active cysteines. This strongly suggests that it lacks thioredoxin activity.

Protein cellular localization

Cytoplasm, cytosol . Cytoplasm, cell cortex . Cytoplasm, myofibril, sarcomere, Z line . Note=Under the plasma membrane (By similarity). After PMA stimulation, GLRX3 and PRKCQ/PKC-theta translocate to a more extended submembrane area (By similarity). In the Z line, found associated with CSRP3 (By similarity). .

Research area

All research areas>Synthesis and Degradation>PICOT
(View all antibody categories related to Synthesis and Degradation)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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