Anti-GRIA1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-GRIA1 Antibody (CSB-PA009898ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Glutamate receptor 1 Antibody,GluR-1 Antibody,AMPA-selective glutamate receptor 1 Antibody,GluR-A Antibody,GluR-K1 Antibody,Glutamate receptor ionotropic Antibody, AMPA 1 Antibody,GluA1 Antibody,GRIA1 Antibody,GLUH1 Antibody, GLUR1 Antibody

More alternative names for the antibody
GLUR 1 antibody| GLUR A antibody|AMPA 1 antibody|AMPA selective glutamate receptor 1 antibody|AMPA-selective glutamate receptor 1 antibody|GluA1 antibody|GLUH1 antibody|GluR K1 antibody|GluR-1 antibody|GluR-A antibody|GluR-K1 antibody|GLUR1 antibody|GLURA antibody|GluRK1 antibody|Glutamate receptor 1 antibody|Glutamate receptor ionotropic AMPA 1 antibody|Glutamate receptor ionotropic antibody|Glutamate receptor, ionotropic, AMPA 1 antibody|Gria1 antibody|GRIA1_HUMAN antibody|HBGR1 antibody|MGC133252 antibody|OTTHUMP00000160643 antibody|OTTHUMP00000165781 antibody|OTTHUMP00000224241 antibody|OTTHUMP00000224242 antibody|OTTHUMP00000224243 antibody
Anti-Glutamate Receptor 1 (AMPA subtype) antibody (ab31232)
Close sc-7609|sc-13152|sc-55509|sc-28799|sc-33612|sc-7610|sc-7611|sc-517202|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-GRIA1 Antibody

Catalogue No.

CSB-PA009898ESR1HU

Reactivity

Human

Immunogen

Recombinant human Glutamate receptor 1 protein (19-300AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

101 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:2890( Human), Entrez Gene:14799( Mouse), Entrez Gene:50592( Rat), Omim:138248( Human), SwissProt:P42261( Human), SwissProt:P23818( Mouse), SwissProt:P19490( Rat), Unigene:519693( Human), Unigene:737709( Human), Unigene:4920( Mouse), Unigene:29971( Rat)

Protein function

Ionotropic glutamate receptor. L-glutamate acts as an excitatory neurotransmitter at many synapses in the central nervous system. Binding of the excitatory neurotransmitter L-glutamate induces a conformation change, leading to the opening of the cation channel, and thereby converts the chemical signal to an electrical impulse. The receptor then desensitizes rapidly and enters a transient inactive state, characterized by the presence of bound agonist. In the presence of CACNG4 or CACNG7 or CACNG8, shows resensitization which is characterized by a delayed accumulation of current flux upon continued application of glutamate. .

Protein tissue specificity

Widely expressed in brain.

Protein sequence and domain

Belongs to the glutamate-gated ion channel (TC 1.A.10.1) family. GRIA1 subfamily. The M4 transmembrane segment mediates tetramerization and is required for cell surface expression.

Protein post-translational modifications

Palmitoylated. Depalmitoylated upon glutamate stimulation. Cys-603 palmitoylation leads to Golgi retention and decreased cell surface expression. In contrast, Cys-829 palmitoylation does not affect cell surface expression but regulates stimulation-dependent endocytosis (By similarity). .; Phosphorylated at Ser-645. Phosphorylated at Ser-710 by PKC. Phosphorylated at Ser-849 by PKC, PKA and CAMK2. Phosphorylated at Ser-863 by PKC, PKA and PRKG2. .

Protein cellular localization

Cell membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane ; Multi-pass membrane protein . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . Cell projection, dendrite . Cell projection, dendritic spine . Note=Interaction with CACNG2, CNIH2 and CNIH3 promotes cell surface expression. .

Note

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Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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