Anti-H2AFZ Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-H2AFZ Antibody (CSB-PA010100ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

H2A/z Antibody,H2AFZ Antibody,H2AZ Antibody

More alternative names for the antibody
H2A/z antibody|H2afz antibody|H2AZ antibody|H2AZ_HUMAN antibody|Histone H2A.Z antibody
Acetyl anti-H2A.Z (K4 + K7 + K11) antibody – ChIP Grade (ab18262)
Close sc-67218|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-H2AFZ Antibody

Catalogue No.

CSB-PA010100ESR2HU

Reactivity

Human

Immunogen

Recombinant human Histone H2A.Z protein (1-128AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

13 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3015( Human), Entrez Gene:51788( Mouse), Omim:142763( Human), SwissProt:P02272( Chicken), SwissProt:P0C0S5( Human), SwissProt:P0C0S6( Mouse), Unigene:119192( Human), Unigene:117541( Mouse), Unigene:372513( Mouse)

Protein function

Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. .

Protein sequence and domain

Belongs to the histone H2A family.

Protein post-translational modifications

Monoubiquitination of Lys-122 gives a specific tag for epigenetic transcriptional repression. .; Acetylated on Lys-5, Lys-8 and Lys-12 during interphase. Acetylation disappears at mitosis (By similarity). .; Monomethylated on Lys-5 and Lys-8 by SETD6. SETD6 predominantly methylates Lys-8, lys-5 being a possible secondary site. .; Not phosphorylated. .

Protein cellular localization

Nucleus. Chromosome.

Research area

All research areas>Transcription Regulators>Histone
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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