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Rabbit Anti-HADH Antibody (CSB-PA614992ESR2HU)
Supplier: CUSABIO BIOTECH CO.
Hydroxyacyl-coenzyme A dehydrogenase Antibody,mitochondrial Antibody,HCDH Antibody,Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase Antibody,Short-chain 3-hydroxyacyl-CoA dehydrogenase Antibody,HADH Antibody,HAD Antibody,HADHSC Antibody,SCHAD AntibodyMore alternative names for the antibody
3 hydroxyacyl Coenzyme A dehydrogenase antibody|HAD antibody|HADH antibody|HADH1 antibody|HADHSC antibody|HADHSC, formerly antibody|HADSC, formerly antibody|HCDH antibody|HCDH_HUMAN antibody|HHF4 antibody|Hydroxyacyl CoA dehydrogenase antibody|Hydroxyacyl-coenzyme A dehydrogenase antibody|hydroxyacyl-coenzyme A dehydrogenase, mitochondrial antibody|L 3 hydroxyacyl Coenzyme A dehydrogenase short chain antibody|M SCHAD antibody|Medium and short chain L 3 hydroxyacyl coenzyme A dehydrogenase antibody|Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase antibody|MGC8392 antibody|mitochondrial antibody|MSCHAD antibody|OTTHUMP00000162626 antibody|OTTHUMP00000219688 antibody|SCHAD antibody|SCHAD, formerly antibody|Short chain 3 hydroxyacyl CoA dehydrogenase mitochondrial antibody|short chain 3-hydroxyacyl-coa dehydrogenase antibody|Short-chain 3-hydroxyacyl-CoA dehydrogenase antibody
Anti-HADHSC antibody – Azide free (ab37673)
Anti-HADHSC antibody – Azide free (ab37673)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial protein (1-314AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=3033" target="_blank">Entrez Gene:3033( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=15107" target="_blank">Entrez Gene:15107( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=113965" target="_blank">Entrez Gene:113965( Rat)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/601609" target="_blank">Omim:601609( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q16836" target="_blank">SwissProt:Q16836( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q61425" target="_blank">SwissProt:Q61425( Mouse)</a>, <a href="http://www.uniprot.org/uniprot/Q9WVK7" target="_blank">SwissProt:Q9WVK7( Rat)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=438289" target="_blank">Unigene:438289( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=260164" target="_blank">Unigene:260164( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Rn&CID=92789" target="_blank">Unigene:92789( Rat)</a>
|Protein function|| |
Plays an essential role in the mitochondrial beta-oxidation of short chain fatty acids. Exerts it highest activity toward 3-hydroxybutyryl-CoA.
|Protein tissue specificity|| |
Expressed in liver, kidney, pancreas, heart and skeletal muscle.
|Involvement in disease|| |
3-alpha-hydroxyacyl-CoA dehydrogenase deficiency (HADH deficiency) [MIM:231530]: A metabolic disorder with various clinical presentations including hypoglycemia, hepatoencephalopathy, myopathy or cardiomyopathy, and in some cases sudden death. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Familial hyperinsulinemic hypoglycemia 4 (HHF4) [MIM:609975]: Most common cause of persistent hypoglycemia in infancy. Unless early and aggressive intervention is undertaken, brain damage from recurrent episodes of hypoglycemia may occur. HHF4 should be easily recognizable by analysis of acylcarnitine species and that this disorder responds well to treatment with diazoxide. It provides the first 'experiment of nature' that links impaired fatty acid oxidation to hyperinsulinism and that provides support for the concept that a lipid signaling pathway is implicated in the control of insulin secretion. . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the 3-hydroxyacyl-CoA dehydrogenase family.
|Protein post-translational modifications|| |
Succinylation at Lys-81, adjacent to a coenzyme A binding site. Desuccinylated by SIRT5 (By similarity). .
|Protein cellular localization|| |
|Research area|| |
<a href="https://antibodyplus.com/research-areas/">All research areas</a>><a href="https://antibodyplus.com/Synthesis-and-Degradation/">Synthesis and Degradation</a>><a href="https://antibodyplus.com/product-tag/HADHSC/">HADHSC</a><br><a href="https://antibodyplus.com/product-tag/Synthesis-and-Degradation/"> (View all antibody categories related to Synthesis and Degradation)</a>
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CUSABIO BIOTECH CO.
|Product type|| |
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