Anti-HARS Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC,IP
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-HARS Antibody (CSB-PA010137ESR2HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Histidyl-tRNA synthetase Antibody,HisRS Antibody,HARS Antibody,HRS Antibody

More alternative names for the antibody
cytoplasmic antibody|EC 6.1.1.21 antibody|FLJ20491 antibody|HARS antibody|HisRS antibody|Histidine tRNA ligase, cytoplasmic antibody|histidine translase antibody|Histidine tRNA ligase antibody|Histidine–tRNA ligase antibody|Histidyl tRNA synthetase antibody|Histidyl-tRNA synthetase antibody|HRS antibody|Human histidyl tRNA synthetase homolog (HO3) mRNA complete cds antibody|SYHC_HUMAN antibody|USH3B antibody
Anti-TXNRD1 antibody [EPNCIR129] (ab124954)
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Recommended applications: ELISA, WB, IHC, IP

Recommended dilution: Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Recommended protocols: check protocols

Name

Anti-HARS Antibody

Catalogue No.

CSB-PA010137ESR2HU

Reactivity

Human

Immunogen

Recombinant human Histidine–tRNA ligase, cytoplasmic protein (1-180AA)

Host

Rabbit

Applications

ELISA, WB, IHC, IP

Recommended dilution

Recommended dilution:WB:1:1000-1:5000,IHC:1:20-1:200,IP:1:200-1:2000

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

57 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:7296( Human), Entrez Gene:50493( Mouse), Entrez Gene:58819( Rat), Omim:601112( Human), SwissProt:Q16881( Human), SwissProt:Q9JMH6( Mouse), SwissProt:O89049( Rat), Unigene:210155( Mouse), Unigene:471159( Mouse), Unigene:67581( Rat)

Protein function

Cytoplasmic histidine–tRNA ligase (Probable). Plays a role in axon guidance. .

Protein tissue specificity

Brain, heart, liver and kidney.

Involvement in disease

Usher syndrome 3B (USH3B) [MIM:614504]: A syndrome characterized by progressive vision and hearing loss during early childhood. Some patients have the so-called ‘Charles Bonnet syndrome,’ involving decreased visual acuity and vivid visual hallucinations. USH is a genetically heterogeneous condition characterized by the association of retinitis pigmentosa with sensorineural deafness. Age at onset and differences in auditory and vestibular function distinguish Usher syndrome type 1 (USH1), Usher syndrome type 2 (USH2) and Usher syndrome type 3 (USH3). USH3 is characterized by postlingual, progressive hearing loss, variable vestibular dysfunction, and onset of retinitis pigmentosa symptoms, including nyctalopia, constriction of the visual fields, and loss of central visual acuity, usually by the second decade of life. . Note=The disease is caused by mutations affecting the gene represented in this entry.; Charcot-Marie-Tooth disease 2W (CMT2W) [MIM:616625]: An autosomal dominant, axonal form of Charcot-Marie-Tooth disease, a disorder of the peripheral nervous system, characterized by progressive weakness and atrophy, initially of the peroneal muscles and later of the distal muscles of the arms. Charcot-Marie-Tooth disease is classified in two main groups on the basis of electrophysiologic properties and histopathology: primary peripheral demyelinating neuropathies (designated CMT1 when they are dominantly inherited) and primary peripheral axonal neuropathies (CMT2). Neuropathies of the CMT2 group are characterized by signs of axonal degeneration in the absence of obvious myelin alterations, normal or slightly reduced nerve conduction velocities, and progressive distal muscle weakness and atrophy. CMT2W patients manifest a peripheral neuropathy mainly affecting the lower limbs and resulting in gait difficulties and distal sensory impairment. Most patients also have upper limb involvement. . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the class-II aminoacyl-tRNA synthetase family.

Protein cellular localization

Cytoplasm.

Research area

All research areas>Transcription Regulators>LeuRS
(View all antibody categories related to Transcription Regulators)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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