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Rabbit Anti-HSD11B1 Antibody (CSB-PA010763ESR2HU)
Supplier: CUSABIO BIOTECH CO.
11-beta-hydroxysteroid dehydrogenase 1 Antibody,11-DH Antibody, 11-beta-HSD1 Antibody,HSD11B1 Antibody,HSD11 Antibody, HSD11L AntibodyMore alternative names for the antibody
11 beta HSD 1 antibody|11 beta HSD1 antibody|11 beta hydroxysteroid dehydrogenase 1 antibody|11 DH antibody|11-beta hydroxysteroid dehydrogenase, type 1 antibody|11-beta-HSD1 antibody|11-beta-hydroxysteroid dehydrogenase 1 antibody|11-DH antibody|11DH antibody|Corticosteroid 11 beta dehydrogenase isozyme 1 antibody|Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody|CORTRD2 antibody|DHI1_HUMAN antibody|HDL antibody|HSD 11 antibody|HSD11 antibody|HSD11B antibody|HSD11B1 antibody|HSD11L antibody|Hydroxysteroid (11 beta) dehydrogenase antibody|Hydroxysteroid (11 beta) dehydrogenase 1 antibody|MGC13539 antibody|SDR26C1 antibody|short chain dehydrogenase/reductase family 26C, member 1 antibody
Anti-HSD11B1 antibody (ab39364)
Anti-HSD11B1 antibody (ab39364)
Recommended applications: ELISA, WB, IHC
Recommended dilution: Recommended dilution:WB:1:500-2000,IHC:1:20-1:200
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Corticosteroid 11-beta-dehydrogenase isozyme 1 protein (25-292AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
Entrez Gene:3290( Human), Entrez Gene:15483( Mouse), Entrez Gene:25116( Rat), Omim:600713( Human), SwissProt:Q6R0J2( Hamster), SwissProt:P28845( Human), SwissProt:P50172( Mouse), SwissProt:Q7M3I4( Rabbit), SwissProt:P16232( Rat), Unigene:195040( Human), Unigene:28328( Mouse), Unigene:185798( Rat), Unigene:888( Rat)
|Protein function|| |
Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity). .
|Protein tissue specificity|| |
Widely expressed. Highest expression in liver.
|Involvement in disease|| |
Cortisone reductase deficiency (CRD) [MIM:604931]: In CRD, activation of cortisone to cortisol does not occur, resulting in adrenocorticotropin-mediated androgen excess and a phenotype resembling polycystic ovary syndrome (PCOS). . Note=The disease is caused by mutations affecting the gene represented in this entry.
|Protein sequence and domain|| |
Belongs to the short-chain dehydrogenases/reductases (SDR) family.
|Protein post-translational modifications|| |
|Protein cellular localization|| |
Endoplasmic reticulum membrane ; Single-pass type II membrane protein .
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CUSABIO BIOTECH CO.
|Product type|| |
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