Anti-HSD11B1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-HSD11B1 Antibody (CSB-PA010763ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

11-beta-hydroxysteroid dehydrogenase 1 Antibody,11-DH Antibody, 11-beta-HSD1 Antibody,HSD11B1 Antibody,HSD11 Antibody, HSD11L Antibody

More alternative names for the antibody
11 beta HSD 1 antibody|11 beta HSD1 antibody|11 beta hydroxysteroid dehydrogenase 1 antibody|11 DH antibody|11-beta hydroxysteroid dehydrogenase, type 1 antibody|11-beta-HSD1 antibody|11-beta-hydroxysteroid dehydrogenase 1 antibody|11-DH antibody|11DH antibody|Corticosteroid 11 beta dehydrogenase isozyme 1 antibody|Corticosteroid 11-beta-dehydrogenase isozyme 1 antibody|CORTRD2 antibody|DHI1_HUMAN antibody|HDL antibody|HSD 11 antibody|HSD11 antibody|HSD11B antibody|HSD11B1 antibody|HSD11L antibody|Hydroxysteroid (11 beta) dehydrogenase antibody|Hydroxysteroid (11 beta) dehydrogenase 1 antibody|MGC13539 antibody|SDR26C1 antibody|short chain dehydrogenase/reductase family 26C, member 1 antibody
Anti-HSD11B1 antibody (ab39364)
Close sc-19259|sc-20175|sc-19257|

Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-HSD11B1 Antibody

Catalogue No.

CSB-PA010763ESR1HU

Reactivity

Human

Immunogen

Recombinant human Corticosteroid 11-beta-dehydrogenase isozyme 1 protein (25-292AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

32 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:3290( Human), Entrez Gene:15483( Mouse), Entrez Gene:25116( Rat), Omim:600713( Human), SwissProt:Q6R0J2( Hamster), SwissProt:P28845( Human), SwissProt:P50172( Mouse), SwissProt:Q7M3I4( Rabbit), SwissProt:P16232( Rat), Unigene:195040( Human), Unigene:28328( Mouse), Unigene:185798( Rat), Unigene:888( Rat)

Protein function

Catalyzes reversibly the conversion of cortisol to the inactive metabolite cortisone. Catalyzes reversibly the conversion of 7-ketocholesterol to 7-beta-hydroxycholesterol. In intact cells, the reaction runs only in one direction, from 7-ketocholesterol to 7-beta-hydroxycholesterol (By similarity). .

Protein tissue specificity

Widely expressed. Highest expression in liver.

Involvement in disease

Cortisone reductase deficiency (CRD) [MIM:604931]: In CRD, activation of cortisone to cortisol does not occur, resulting in adrenocorticotropin-mediated androgen excess and a phenotype resembling polycystic ovary syndrome (PCOS). . Note=The disease is caused by mutations affecting the gene represented in this entry.

Protein sequence and domain

Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Protein post-translational modifications

Glycosylated. .

Protein cellular localization

Endoplasmic reticulum membrane ; Single-pass type II membrane protein .

Research area

All research areas>Kinases and Phosphatases>11 beta-HSD
(View all antibody categories related to Kinases and Phosphatases)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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