Anti-HTR2B Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-HTR2B Antibody (CSB-PA010888ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

5-HT-2B Antibody,5-HT2B Antibody,Serotonin receptor 2B Antibody,HTR2B Antibody

More alternative names for the antibody
5 HT 2B antibody|5 HT 2B receptor antibody|5 HT(2B) antibody|5 HT2B antibody|5 hydroxytryptamine (serotonin) receptor 2B antibody|5 hydroxytryptamine (serotonin) receptor 2B G protein coupled antibody|5 hydroxytryptamine 2B receptor antibody|5 hydroxytryptamine receptor 2B antibody|5-HT-2B antibody|5-HT2B antibody|5-hydroxytryptamine receptor 2B antibody|5HT(2B) antibody|5HT2B_HUMAN antibody|5HT2F antibody|Htr 2b antibody|Htr2b antibody|NP75 protein antibody|SEROTONIN 5HT2B RECEPTOR antibody|Serotonin receptor 2B antibody|Stomach fundus serotonin receptor antibody
Anti-5HT2B Receptor antibody – Cytoplasmic domain (ab140495)
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Recommended applications: ELISA, IHC

Recommended dilution: Recommended dilution:IHC:1:20-1:200

Recommended protocols: check protocols

Name

Anti-HTR2B Antibody

Catalogue No.

CSB-PA010888ESR1HU

Reactivity

Human

Immunogen

Recombinant human 5-hydroxytryptamine receptor 2B protein (382-481AA)

Host

Rabbit

Applications

ELISA, IHC

Recommended dilution

Recommended dilution:IHC:1:20-1:200

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

54 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:407135( Cow), Entrez Gene:3357( Human), Entrez Gene:396837( Pig), Omim:601122( Human), SwissProt:P41595( Human), SwissProt:Q29005( Pig), Unigene:421649( Human)

Protein function

G-protein coupled receptor for 5-hydroxytryptamine (serotonin). Also functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Beta-arrestin family members inhibit signaling via G proteins and mediate activation of alternative signaling pathways. Signaling activates a phosphatidylinositol-calcium second messenger system that modulates the activity of phosphatidylinositol 3-kinase and down-stream signaling cascades and promotes the release of Ca(2+) ions from intracellular stores. Plays a role in the regulation of dopamine and 5-hydroxytryptamine release, 5-hydroxytryptamine uptake and in the regulation of extracellular dopamine and 5-hydroxytryptamine levels, and thereby affects neural activity. May play a role in the perception of pain. Plays a role in the regulation of behavior, including impulsive behavior. Required for normal proliferation of embryonic cardiac myocytes and normal heart development. Protects cardiomyocytes against apoptosis. Plays a role in the adaptation of pulmonary arteries to chronic hypoxia. Plays a role in vasoconstriction. Required for normal osteoblast function and proliferation, and for maintaining normal bone density. Required for normal proliferation of the interstitial cells of Cajal in the intestine. .

Protein tissue specificity

Ubiquitous. Detected in liver, kidney, heart, pulmonary artery, and intestine. Detected at lower levels in blood, placenta and brain, especially in cerebellum, occipital cortex and frontal cortex. .

Protein sequence and domain

Belongs to the G-protein coupled receptor 1 family. Ligands are bound in a hydrophobic pocket formed by the transmembrane helices.

Protein cellular localization

Cell membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome .

Research area

All research areas>Neurobiology Antibodies>SR
(View all antibody categories related to Neurobiology Antibodies)

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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