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Rabbit Anti-HVCN1 Antibody (CSB-PA846602ESR1HU)
Supplier: CUSABIO BIOTECH CO.
Voltage-gated hydrogen channel 1 Antibody,Hydrogen voltage-gated channel 1 Antibody,HV1 Antibody,Voltage sensor domain-only protein Antibody,HVCN1 Antibody,VSOP Antibody,UNQ578/PRO1140 AntibodyMore alternative names for the antibody
HV 1 antibody|HV1 antibody|HVCN 1 antibody|HVCN1 antibody|HVCN1_HUMAN antibody|Hydrogen voltage gated channel 1 antibody|Hydrogen voltage-gated channel 1 antibody|Voltage gated hydrogen channel 1 antibody|Voltage sensor domain only protein antibody|Voltage sensor domain-only protein antibody|Voltage-gated hydrogen channel 1 antibody|VSOP antibody
Anti-HVCN1 antibody (ab117520)
Anti-HVCN1 antibody (ab117520)
Recommended applications: ELISA, WB, IHC
Recommended dilution: User optimized
Recommended protocols: check protocols
|Catalogue No.|| |
Recombinant human Voltage-gated hydrogen channel 1 protein (1-100AA)
ELISA, WB, IHC
|Recommended dilution|| |
|Molecular weight|| |
Antigen Affinity Purified
Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.
|Database links|| |
<a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=84329" target="_blank">Entrez Gene:84329( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=gene&cmd=Retrieve&dopt=Graphics&list_uids=74096" target="_blank">Entrez Gene:74096( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/omim/611227" target="_blank">Omim:611227( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q96D96" target="_blank">SwissProt:Q96D96( Human)</a>, <a href="http://www.uniprot.org/uniprot/Q3U2S8" target="_blank">SwissProt:Q3U2S8( Mouse)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=211511" target="_blank">Unigene:211511( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Hs&CID=334637" target="_blank">Unigene:334637( Human)</a>, <a href="http://www.ncbi.nlm.nih.gov/UniGene/clust.cgi?ORG=Mm&CID=28804" target="_blank">Unigene:28804( Mouse)</a>
|Protein function|| |
Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. .
|Protein tissue specificity|| |
Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. .
|Protein sequence and domain|| |
Belongs to the hydrogen channel family. The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Unlike other voltage-gated ion channels it lacks the pore domain.; The C-terminal coiled coil region mediates homodimerization and cooperative channel gating. It is essential for normal subcellular localization.
|Protein post-translational modifications|| |
Phosphorylation may enhance channel gating. .
|Protein cellular localization|| |
Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types.
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CUSABIO BIOTECH CO.
|Product type|| |
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