Anti-HVCN1 Antibody

$99.00$319.00

Reactivity: Human
Applications: ELISA,WB,IHC
Conjugation: Various
Supplier: CUSABIO BIOTECH CO.

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Rabbit Anti-HVCN1 Antibody (CSB-PA846602ESR1HU)

Supplier: CUSABIO BIOTECH CO.

Alternative names:

Voltage-gated hydrogen channel 1 Antibody,Hydrogen voltage-gated channel 1 Antibody,HV1 Antibody,Voltage sensor domain-only protein Antibody,HVCN1 Antibody,VSOP Antibody,UNQ578/PRO1140 Antibody

More alternative names for the antibody
HV 1 antibody|HV1 antibody|HVCN 1 antibody|HVCN1 antibody|HVCN1_HUMAN antibody|Hydrogen voltage gated channel 1 antibody|Hydrogen voltage-gated channel 1 antibody|Voltage gated hydrogen channel 1 antibody|Voltage sensor domain only protein antibody|Voltage sensor domain-only protein antibody|Voltage-gated hydrogen channel 1 antibody|VSOP antibody
Anti-HVCN1 antibody (ab117520)
Close sc-136712|sc-136714|

Recommended applications: ELISA, WB, IHC

Recommended dilution: User optimized

Recommended protocols: check protocols

Name

Anti-HVCN1 Antibody

Catalogue No.

CSB-PA846602ESR1HU

Reactivity

Human

Immunogen

Recombinant human Voltage-gated hydrogen channel 1 protein (1-100AA)

Host

Rabbit

Applications

ELISA, WB, IHC

Recommended dilution

User optimized

Clonality

Polyclonal

Conjugation

unconjugated

Isotype

IgG

Molecular weight

31 kDa

Purification

Antigen Affinity Purified

Storage

Shipped at 4 Celcius Degree. Upon delivery aliquot and store at -20 Celcius Degree or -80 Celcius Degree. Avoid repeated freeze.

Database links

Entrez Gene:84329( Human), Entrez Gene:74096( Mouse), Omim:611227( Human), SwissProt:Q96D96( Human), SwissProt:Q3U2S8( Mouse), Unigene:211511( Human), Unigene:334637( Human), Unigene:28804( Mouse)

Protein function

Mediates the voltage-dependent proton permeability of excitable membranes. Forms a proton-selective channel through which protons may pass in accordance with their electrochemical gradient. Proton efflux, accompanied by membrane depolarization, facilitates acute production of reactive oxygen species in phagocytosis. .

Protein tissue specificity

Enriched in immune tissues, such as lymph nodes, B-lymphocytes, monocytes and spleen. .

Protein sequence and domain

Belongs to the hydrogen channel family. The segment S4 is probably the voltage-sensor and is characterized by a series of positively charged amino acids at every third position. Unlike other voltage-gated ion channels it lacks the pore domain.; The C-terminal coiled coil region mediates homodimerization and cooperative channel gating. It is essential for normal subcellular localization.

Protein post-translational modifications

Phosphorylation may enhance channel gating. .

Protein cellular localization

Membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Note=Detected mainly at intracellular membranes upon overexpression in HeLa cells (PuMed:20147290), but not in other cell types.

Note

AntibodyPlus provides antibody trial sample for your own antibody validation and collects antibody reviews.

Supplier

CUSABIO BIOTECH CO.

Product type

Primary antibody

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